MYBL2 antibody (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2) (N-Term)

Details for Product anti-MYBL2 Antibody No. ABIN2792568
Target
Binding Specificity
N-Term
19
15
10
8
8
5
4
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Rabbit, Rat, Zebrafish (Danio rerio)
93
75
67
4
4
3
3
3
3
2
1
1
Host
Rabbit
85
8
7
Clonality
Polyclonal
Conjugate
This MYBL2 antibody is un-conjugated
7
5
5
4
4
4
4
4
4
3
3
3
3
3
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
52
37
32
15
15
10
6
4
2
2
2
1
Options
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human MYBL2
Sequence RCEDLDELHY QDTDSDVPEQ RDSKCKVKWT HEEDEQLRAL VRQFGQQDWK
Cross-Reactivity Cow (Bovine), Dog (Canine), Chicken, Human, Rat (Rattus)
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Rabbit: 92%, Rat: 78%, Zebrafish: 83%
Characteristics This is a rabbit polyclonal antibody against MYBL2. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Target
Alternative Name MYBL2 (MYBL2 Antibody Abstract)
Background Myb-Related Protein B (MYBL2), a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined.
Alias Symbols: BMYB, B-MYB
Protein Interaction Partner: CCNA1, CDK2, CCNE1, LIN54, SPTBN1, SPTA1, FLNA, CLTC, CLTA, LIN9, UBE2D4, CXCR4, LIN52, LIN37, RBL1, RBBP4, SUMO2, MAP1LC3B, MAPK6, NLK, HIPK2, CREBBP, ZBTB9, TRIM15, LZTR1, CDK9, ZNF622, UBB, TTF2, EP300, SND1, SKP2, MYBL2, NCOR1, NCOR2, PARP1, CCND1, CC
Protein Size: 700
Molecular Weight 79 kDa
Gene ID 4605
NCBI Accession NM_002466, NP_002457
UniProt P10244
Pathways Cell Division Cycle, Mitotic G1-G1/S Phases, Chromatin Binding
Application Notes WB Suggested Anti-MYBL2 Antibody Titration: 0.2-1 µg/mL
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 700 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Images
Image no. 1 for anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (N-Term) antibody (ABIN2792568) Human Spermatophore
Image no. 2 for anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (N-Term) antibody (ABIN2792568) WB Suggested Anti-MYBL2 Antibody Titration: 0.2-1 ug/ml Positive Control: HepG2 ce...
Product cited in: Tashiro, Sumi, Uozumi, Shimizu, Nakamura: "B-Myb-dependent regulation of c-Myc expression by cytosolic phospholipase A2." in: The Journal of biological chemistry, Vol. 279, Issue 17, pp. 17715-22, 2004 (PubMed).