MYBL2 antibody (N-Term)

Catalog No. ABIN2792568

There is 1 publication for this product available. The Rabbit Polyclonal anti-MYBL2 antibody is suitable to detect MYBL2 in samples from Human, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio). It has been validated for WB and IHC.

Quick Overview for MYBL2 antibody (N-Term) (ABIN2792568)

Target: MYBL2 (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2))

Reactivity: Human, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYBL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MYBL2 Antibody

Binding Specificity: N-Term

Purpose: MYBL2 Antibody - N-terminal region

Sequence: RCEDLDELHY QDTDSDVPEQ RDSKCKVKWT HEEDEQLRAL VRQFGQQDWK

Cross-Reactivity: Cow (Bovine), Dog (Canine), Chicken, Human, Rat (Rattus)

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Rabbit: 92%, Rat: 78%, Zebrafish: 83%

Characteristics: This is a rabbit polyclonal antibody against MYBL2. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MYBL2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-MYBL2 antibody (ABIN2792568)

Tashiro, Sumi, Uozumi, Shimizu, Nakamura: "B-Myb-dependent regulation of c-Myc expression by cytosolic phospholipase A2." in: The Journal of biological chemistry, Vol. 279, Issue 17, pp. 17715-22, (2004) (PubMed).

Target Details for MYBL2

Target: MYBL2 (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2))

Alternative Name: MYBL2

Background:

Background Information: Myb-Related Protein B (MYBL2), a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined.

Gene Name: V-myb myeloblastosis viral oncogene homolog (avian)-like 2

Alternative Symbols: BMYB, B-MYB

Protein Name: Myb-related protein B

Molecular Weight: 79kDa

Gene ID: 4605

NCBI Accession: NP_002457

UniProt: P10244

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases, Chromatin Binding