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CD11b antibody (APC)

ITGAM Reactivity: Human FACS Host: Mouse Monoclonal ICRF44 APC
Catalog No. ABIN375392
  • Target See all CD11b (ITGAM) Antibodies
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Reactivity
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    Human
    Host
    • 134
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    Mouse
    Clonality
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    Monoclonal
    Conjugate
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    This CD11b antibody is conjugated to APC
    Application
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    Flow Cytometry (FACS)
    Specificity
    Human/Porcine/Rhesus/Cynomolgus/Chimpanzee/Baboon CD11b, Mr 165 kDa
    Characteristics
    Mouse Anti-Human CD11b-APC
    Purification
    Purified
    Immunogen
    Rheumatoid synovial cells and human monocytes
    Clone
    ICRF44
    Isotype
    IgG1
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    Discover our top product ITGAM Primary Antibody
  • Application Notes
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , WB - Reported in literature , Block - Reported in literature
    • Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, PE, APC, SPRD, PACBLU, AF488 and AF647 10 L/106 cells conjugates For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Comment

    Blocking Studies

    Restrictions
    For Research Use only
  • Buffer
    25 tests in 0.25 mL or 100 tests in 1.0 mL of PBS/Sodium azide and a stabilizing agent
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze!
    Protect conjugated products from light.

    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C
  • Target
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Alternative Name
    CD11b (ITGAM Products)
    Synonyms
    CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody
    Background
    CD11b is the 165 kDa α M chain which combines with the CD18 β 2 integrin subunit to form the Mac-1 heterodimer. It is expressed on activated lymphocytes, monocytes, granulocytes and a subset of NK cells. CD11b/Mac-1 α functions in cell-cell and cell-substrate interactions and is a ligand for C3bi, CD50 (ICAM-3), CD54 (ICAM-1) and CD102 (ICAM-2).
    Pathways
    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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