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AXL antibody (AXL Receptor tyrosine Kinase) (AA 13-44)

Details for Product anti-AXL Antibody No. ABIN391876, Supplier: Log in to see
Antigen
  • JTK11
  • UFO
  • AI323647
  • Ark
  • Tyro7
  • Ufo
Alternatives
anti-Human AXL antibody for Western Blotting
Epitope
AA 13-44, N-Term
36
28
16
15
15
14
14
12
8
6
6
5
5
5
4
4
4
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
186
65
53
3
Host
Rabbit
153
41
4
2
1
Clonality (Clone)
Polyclonal ()
Conjugate
This AXL antibody is un-conjugated
10
9
9
8
7
6
2
2
2
2
2
2
2
2
2
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
153
101
51
27
22
21
13
7
6
5
2
1
1
1
Supplier
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Immunogen This AXL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-44 AA from the N-terminal region of human AXL.
Clone RB1481
Isotype Ig
Specificity This AXL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14~44 amino acids from the N-terminal region of human AXL.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name AXL (AXL Antibody Abstract)
Background AXL, a member of the AXL/UFO subfamily of Tyr protein kinases, may function as a signal transducer between specific cell types of mesodermal origin. This Type I membrane protein has transforming potential in patients with chronic myeloproliferative disorder or chronic myelocytic leukemia. The protein contains 2 putative fibronectin type III domains and 2 putative immunoglobulin-like C2-type domains.
Synonyms: Tyrosine-protein kinase receptor UFO precursor, AXL oncogene
Molecular Weight 97374 DA
Gene ID 558
UniProt P30530
Research Area Phospho-specific antibodies, Protein Modifications, Cell Structure, Cancer
Pathways RTK Signaling
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-AXL antibody (AXL Receptor tyrosine Kinase) (AA 13-44) (ABIN391876) Western blot analysis of anti-AXL N-term Pab (ABIN391876) in SKBR3 cell lysate. AXL (...
Immunohistochemistry (IHC) image for anti-AXL antibody (AXL Receptor tyrosine Kinase) (AA 13-44) (ABIN391876) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Flow Cytometry (FACS) image for anti-AXL antibody (AXL Receptor tyrosine Kinase) (AA 13-44) (ABIN391876) Flow cytometric analysis of WiDr cells using AXL Antibody (N-term) (bottom histogram)...
Background publications Lee, Strunk, Spritz: "A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes." in: Oncogene, Vol. 8, Issue 12, pp. 3403-10, 1993 (PubMed).

Partanen, Mäkelä, Alitalo et al.: "Putative tyrosine kinases expressed in K-562 human leukemia cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 22, pp. 8913-7, 1991 (PubMed).

Janssen, Schulz, Steenvoorden et al.: "A novel putative tyrosine kinase receptor with oncogenic potential." in: Oncogene, Vol. 6, Issue 11, pp. 2113-20, 1991 (PubMed).

OBryan, Frye, Cogswell et al.: "axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase." in: Molecular and cellular biology, Vol. 11, Issue 10, pp. 5016-31, 1991 (PubMed).