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KIT antibody (AA 912-941)
KIT
Reactivity: Human, Mouse
WB, IHC (p)
Host: Rabbit
Polyclonal
RB1559-RB1560
unconjugated
Product Details anti-KIT Antibody
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Target
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KIT
(Mast/stem Cell Growth Factor Receptor (KIT))
Binding Specificity
All epitopes for KIT antibodies
AA 912-941
Reactivity
All reactivities for KIT antibodies
Human, Mouse
Host
All hosts for KIT antibodies
Rabbit
Clonality
All clonalities for KIT antibodies
Polyclonal
Conjugate
All conjugates for KIT antibodies
This KIT antibody is un-conjugated
Application
All applications for KIT antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Predicted Reactivity
B, Pig
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This c-KIT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 912-941 amino acids of human c-KIT.
Clone
RB1559-RB1560
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
WB: 1:1000. WB: 1:2000. IHC-P: 1:100
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid freeze-thaw cycles.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
Expiry Date
6 months
Target Details for KIT
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Target
KIT
(Mast/stem Cell Growth Factor Receptor (KIT))
Alternative Name
c-KIT (KIT Products )
Synonyms
C-Kit antibody, CD117 antibody, PBT antibody, SCFR antibody, Bs antibody, Fdc antibody, Gsfsco1 antibody, Gsfsco5 antibody, Gsfsow3 antibody, SCO1 antibody, SCO5 antibody, SOW3 antibody, Ssm antibody, Tr-kit antibody, W antibody, c-KIT antibody, c-kit antibody, MGF antibody, KIT antibody, C-KIT antibody, kit antibody, receptor antibody, sparse antibody, Xkl-1 antibody, kit-a antibody, kit-b antibody, kl1-A antibody, krk1 antibody, pbt antibody, scfr antibody, KIT proto-oncogene receptor tyrosine kinase antibody, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a antibody, KIT proto-oncogene receptor tyrosine kinase S homeolog antibody, KIT antibody, Kit antibody, kita antibody, kit antibody, kit.S antibody
Background
KIT encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.
Molecular Weight
109865
Gene ID
3815
NCBI Accession
NP_000213 , NP_001087241
UniProt
P10721
Pathways
RTK Signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Sensory Perception of Sound , Stem Cell Maintenance , Production of Molecular Mediator of Immune Response , Regulation of long-term Neuronal Synaptic Plasticity
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