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RYK antibody (C-Term)

RYK Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB1494 unconjugated
Catalog No. ABIN392051
  • Target See all RYK Antibodies
    RYK (RYK Receptor-Like Tyrosine Kinase (RYK))
    Binding Specificity
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 561-591, C-Term
    Reactivity
    • 72
    • 30
    • 17
    Human
    Host
    • 60
    • 13
    • 3
    • 1
    Rabbit
    Clonality
    • 66
    • 11
    Polyclonal
    Conjugate
    • 32
    • 8
    • 8
    • 7
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RYK antibody is un-conjugated
    Application
    • 65
    • 49
    • 32
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    M
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This RYK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 561-591 amino acids from the C-terminal region of human RYK.
    Clone
    RB1494
    Isotype
    Ig Fraction
    Top Product
    Discover our top product RYK Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Santiago, Oguma, Brown, Laurence: "Noncanonical Wnt signaling promotes osteoclast differentiation and is facilitated by the human immunodeficiency virus protease inhibitor ritonavir." in: Biochemical and biophysical research communications, Vol. 417, Issue 1, pp. 223-30, (2012) (PubMed).

    Keeble, Halford, Seaman, Kee, Macheda, Anderson, Stacker, Cooper: "The Wnt receptor Ryk is required for Wnt5a-mediated axon guidance on the contralateral side of the corpus callosum." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 21, pp. 5840-8, (2006) (PubMed).

  • Target
    RYK (RYK Receptor-Like Tyrosine Kinase (RYK))
    Alternative Name
    RYK (RYK Products)
    Synonyms
    RYK antibody, jtk5 antibody, ryk1 antibody, jtk5a antibody, d3s3195 antibody, wu:fb37b12 antibody, wu:fi05b06 antibody, zgc:158381 antibody, MGC114645 antibody, D3S3195 antibody, JTK5 antibody, JTK5A antibody, RYK1 antibody, AW536699 antibody, ERK-3 antibody, Vik antibody, receptor-like tyrosine kinase antibody, receptor-like tyrosine kinase S homeolog antibody, tyrosine-protein kinase RYK antibody, RYK antibody, ryk antibody, ryk.S antibody, LOC100541106 antibody, Ryk antibody
    Background
    RYK is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. A nine nucleotide insertion in some transcripts results in the SLG variant. It is not established whether this is a product of alternative splicing or a second gene, since evidence for a second gene or pseudogene on chromosome 17 exists.
    Molecular Weight
    67815
    Gene ID
    6259
    NCBI Accession
    NP_001005861, NP_002949
    UniProt
    P34925
    Pathways
    RTK Signaling, WNT Signaling, Regulation of Cell Size
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