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SOCS1 antibody (Suppressor of Cytokine Signaling 1) (N-Term)

Details for Product anti-SOCS1 Antibody No. ABIN453835, Supplier: Log in to see
Antigen
  • CIS1
  • cis1
  • CISH1
  • cish1
  • Cish1
  • Cish7
  • jab
  • JAB
  • LOC100228306
  • Socs-1
  • socs-1
  • SOCS-1
  • SOCS1
  • socs1
  • socs1b
  • SSI-1
  • ssi-1
  • SSI1
  • ssi1
  • TIP3
  • tip3
  • zgc:91868
Alternatives
anti-Human SOCS1 antibody for ELISA
Epitope
N-Term
60
26
13
5
4
3
2
2
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
151
65
55
8
8
4
2
2
1
Host
Rabbit
135
18
10
Clonality
Polyclonal
Conjugate
This SOCS1 antibody is un-conjugated
7
7
6
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
140
55
34
29
11
10
8
7
4
4
2
1
Supplier
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Immunogen KLH conjugated synthetic peptide selected from the N-terminal region of human SOCS1
Specificity This antibody reacts to SOCS1.
Purification Saturated Ammonium Sulfate (SAS) precipitation
Alternative Name SOCS1 (SOCS1 Antibody Abstract)
Background SOCS1 is a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling(SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling.Synonyms: JAB, JAK-binding protein, SOCS-1, SSI-1, SSI1, STAT-induced STAT inhibitor 1, Suppressor of cytokine signaling 1, TIP-3, TIP3, Tec-interacting protein 3
Gene ID 8651
NCBI Accession NP_003736
UniProt O15524
Research Area Chromatin and Nuclear Signaling, Signaling, Cytokines
Pathways JAK-STAT Signaling, Interferon-gamma Pathway, TLR Signaling
Application Notes ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-SOCS1 antibody (Suppressor of Cytokine Signaling 1) (N-Term) (ABIN453835) Western blot analysis of SOCS1 Antibody (N-term) in mouse kidney tissue lysates (35ug...
Background publications Minamoto, Ikegame, Ueno, Narazaki, Naka, Yamamoto, Matsumoto, Saito, Hosoe, Kishimoto: "Cloning and functional analysis of new members of STAT induced STAT inhibitor (SSI) family: SSI-2 and SSI-3." in: Biochemical and biophysical research communications, Vol. 237, Issue 1, pp. 79-83, 1997

Starr, Willson, Viney, Murray, Rayner, Jenkins, Gonda, Alexander, Metcalf, Nicola, Hilton: "A family of cytokine-inducible inhibitors of signalling." in: Nature, Vol. 387, Issue 6636, pp. 917-21, 1997