IFNAR2 antibody (AA 28-40)

Catalog No. ABIN462291

Product Details anti-IFNAR2 Antibody

Target: IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))

Binding Specificity: AA 28-40

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This IFNAR2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human IFNAR2. This antibody is expected to recognise all three reported isoforms (NP_000865.2 , NP_997467.1, NP_997468.1 )

Predicted Reactivity: Percent identity with other species by BLAST analysis: Human (100%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide SYDSPDYTDESCT from an internal region of human IFNAR2 (NP_000865.2 , NP_997467.1, NP_997468.1 ). Percent identity with other species by BLAST analysis: Human (100%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL), Peptide-ELISA (1:32000)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL. Peptide ELISA: antibody detection limit dilution 1:32000.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for IFNAR2

Target: IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))

Alternative Name: IFNAR2 (IFNAR2 Products)

Synonyms: AI747302 antibody, Ifnar-2 antibody, IFN-R antibody, IFN-alpha-REC antibody, IFNABR antibody, IFNARB antibody, IFN-R-2 antibody, IFNBR antibody, interferon alpha and beta receptor subunit 2 antibody, interferon (alpha and beta) receptor 2 antibody, IFNAR2 antibody, Ifnar2 antibody

Background: Name/Gene ID: IFNAR2
Family: Interferon Receptor

Synonyms: IFNAR2, IFN-alpha/beta receptor 2, IFN-alpha-REC, IFN-alpha binding protein, IFN-R, IFN-R-2, IFNARB, Type I interferon receptor 2, IFNABR

Gene ID: 3455

NCBI Accession: NP_000865, NP_997467, NP_997468

UniProt: P48551

Pathways: JAK-STAT Signaling, Hepatitis C