IFNAR2 antibody (AA 165-260)

Catalog No. ABIN721825

This Rabbit Polyclonal antibody specifically detects IFNAR2 in WB, IF, ICC, IHC (p) and IHC (fro). It exhibits reactivity toward Mouse.It has been mentioned in 1 publication

Quick Overview for IFNAR2 antibody (AA 165-260) (ABIN721825)

Target: IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFNAR2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-IFNAR2 Antibody

Binding Specificity: AA 165-260

Purpose: IFNAR2 Polyclonal Antibody

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse IFNAR2

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500), IF(), ICC/IF(1:50-100)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-IFNAR2 antibody (ABIN721825)

Lopušná, Benkóczka, Lupták, Matúšková, Lukáčiková, Ovečková, Režuchová: "Murine gammaherpesvirus targets type I IFN receptor but not type III IFN receptor early in infection." in: Cytokine, Vol. 83, pp. 158-70, (2016) (PubMed).

Target Details for IFNAR2

Target: IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))

Alternative Name: IFNAR2

Background:

Synonyms: Ifnar-2, AI747302, Interferon alpha/beta receptor 2, IFN-R-2, IFN-alpha/beta receptor 2, Type I interferon receptor 2, Ifnar2

Background: Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 2 and 3 may be potent inhibitors of type I IFN receptor activity (By similarity).

Gene ID: 15976

UniProt: O35664

Pathways: JAK-STAT Signaling, Hepatitis C