IFNAR2 antibody (Center)

Catalog No. ABIN2856183

Product Details anti-IFNAR2 Antibody

Target: IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))

Binding Specificity: Center

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFNAR2 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Characteristics: Rabbit Polyclonal antibody to IFNAR2 (interferon (alpha, beta and omega) receptor 2)
IFNAR2 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human IFNAR2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*

Comment:

Positive Control: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-IFNAR2 antibody (ABIN2856183)

Shirozu, Iwano, Ogiso, Suzuki, Balboula, Bai, Kawahara, Kimura, Takahashi, Rulan, Kim, Yanagawa, Nagano, Imakawa, Takahashi: "Estrous cycle stage-dependent manner of type I interferon-stimulated genes induction in the bovine endometrium." in: The Journal of reproduction and development, Vol. 63, Issue 3, pp. 211-220, (2018) (PubMed).

Target Details for IFNAR2

Target: IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))

Alternative Name: IFNAR2 (IFNAR2 Products)

Synonyms: AI747302 antibody, Ifnar-2 antibody, IFN-R antibody, IFN-alpha-REC antibody, IFNABR antibody, IFNARB antibody, IFN-R-2 antibody, IFNBR antibody, interferon alpha and beta receptor subunit 2 antibody, interferon (alpha and beta) receptor 2 antibody, IFNAR2 antibody, Ifnar2 antibody

Background: The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene.

Cellular Localization: Membrane, Single-pass type I membrane protein

Molecular Weight: 58 kDa

Gene ID: 3455

Pathways: JAK-STAT Signaling, Hepatitis C