EPH Receptor B1 antibody (EPHB1)

Details for Product anti-EPHB1 Antibody No. ABIN498198, Supplier: Log in to see
Antigen
  • Xek
  • MGC89790
  • EPHB1
  • Ephb2
  • Erk
  • elk
  • ELK
  • EPHT2
  • Hek6
  • NET
  • 9330129L11
  • AW488255
  • C130099E04Rik
  • Cek6
  • ENSMUSG00000074119
  • Elk
  • Elkh
  • Net
  • CEK6
  • EK6
  • ephb1-a
  • xek
  • EPH receptor B1
  • Eph receptor B1
  • EPHB1
  • ephb1
  • Ephb1
Alternatives
anti-Rat (Rattus) EPH Receptor B1 antibody for Western Blotting
Reactivity
Human, Mouse (Murine), Rat (Rattus)
119
80
71
3
Host
Rabbit
106
15
7
2
Clonality
Polyclonal
Conjugate
This EPH Receptor B1 antibody is un-conjugated
5
5
5
3
3
3
3
3
3
3
3
3
3
3
2
2
2
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
77
40
36
21
21
6
4
3
3
2
1
1
1
Options
Supplier
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Specificity This antibody detects endogenous levels of EphB1/2 protein.
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Also reacts to: EphB2
Purification Affinity chromatography using epitope-specific immunogen
Purity > 95 % (by SDS-PAGE)
Alternative Name EPHB1 (EPHB1 Antibody Abstract)
Background Ephrin receptors bind members of the ephrin ligand family. They are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. They make up the largest subgroup of the receptor tyrosine kinase (RTK) family. Eph receptor B1 (EphB1) and Eph receptor B2 (EphB2) are receptors for ephrin-B family members. Developing and adult neural tissue express nearly all of the Ephrin receptors and ephrin ligands. Ephrins and ephrin receptors also play a significant role in angiogenesis. EphB2 acts as a tumor suppressor.Synonyms: ELK, EPH2, EPHT2, Ephrin type-B receptor 1, HEK6, NET, Tyrosine-protein kinase receptor EPH-2
Molecular Weight approx. 110 kDa
Gene ID 2047
NCBI Accession NP_004432
UniProt P54762
Pathways RTK Signaling
Application Notes Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-EPH Receptor B1 (EPHB1) antibody (ABIN498198) Immunohistochemistry analyzes of EphB1/2 antibody in paraffin-embedded human b...
Western Blotting (WB) image for anti-EPH Receptor B1 (EPHB1) antibody (ABIN498198) Western blot (WB) analysis of EphB1/2 antibody in extracts from sp20...
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