JAK3 antibody

Catalog No. ABIN5581352

Product Details anti-JAK3 Antibody

Target: JAK3 (Janus Kinase 3 (JAK3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This JAK3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Purpose: Mouse monoclonal antibody raised against partial recombinant JAK3.

Cross-Reactivity: Human, Mouse

Immunogen: Recombinant protein corresponding to human JAK3.

Clone: 5H2

Isotype: IgG1

Application Details

Application Notes: ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunofluorescence (1:200-1:1000)
Flow cytometry (1:200-1:400)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In ascites (0.03 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-JAK3 antibody (ABIN5581352)

Sato, Okano, Tanaka-Kubota, Kimura, Miyamoto, Ono, Yamashita, Mitsuiki, Takagi, Imai, Kajiwara, Ebato, Ogata, Oda, Ohara, Kanegane, Morio: "Novel compound heterozygous mutations in a Japanese girl with Janus kinase 3 deficiency." in: Pediatrics international : official journal of the Japan Pediatric Society, Vol. 58, Issue 10, pp. 1076-1080, (2016) (PubMed).

Target Details for JAK3

Target: JAK3 (Janus Kinase 3 (JAK3))

Alternative Name: JAK3 (JAK3 Products)

Synonyms: JAK-3 antibody, JAK3_HUMAN antibody, JAKL antibody, L-JAK antibody, LJAK antibody, fae antibody, wil antibody, RATJAK3 antibody, JAK antibody, Janus kinase 3 antibody, JAK3 antibody, Jak3 antibody

Background: Full Gene Name: Janus kinase 3 (a protein tyrosine kinase, leukocyte)
Synonyms: JAK-3,JAK3_HUMAN,JAKL,L-JAK,LJAK

Gene ID: 3718

Pathways: JAK-STAT Signaling, RTK Signaling, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response