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JAK3 antibody

JAK3 Reactivity: Human, Mouse WB, ELISA, FACS, ICC Host: Mouse Monoclonal 5H2 unconjugated
Catalog No. ABIN969224
  • Target See all JAK3 Antibodies
    JAK3 (Janus Kinase 3 (JAK3))
    Reactivity
    • 88
    • 49
    • 19
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 85
    • 5
    Mouse
    Clonality
    • 70
    • 20
    Monoclonal
    Conjugate
    • 33
    • 8
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This JAK3 antibody is un-conjugated
    Application
    • 50
    • 28
    • 22
    • 14
    • 14
    • 11
    • 8
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human JAK3 expressed in E. coli.
    Clone
    5H2
    Isotype
    IgG1
    Top Product
    Discover our top product JAK3 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Wood, Goodman, Uckun: "Jak3 expression and genomic sequence in pediatric acute lymphoblastic leukemia." in: Leukemia & lymphoma, Vol. 43, Issue 12, pp. 2355-62, (2003) (PubMed).

  • Target
    JAK3 (Janus Kinase 3 (JAK3))
    Alternative Name
    JAK3 (JAK3 Products)
    Synonyms
    JAK-3 antibody, JAK3_HUMAN antibody, JAKL antibody, L-JAK antibody, LJAK antibody, fae antibody, wil antibody, RATJAK3 antibody, JAK antibody, Janus kinase 3 antibody, JAK3 antibody, Jak3 antibody
    Background

    Description: JAK3, Janus kinase 3. It is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

    Aliases: JAKL, LJAK

    Molecular Weight
    125 kDa
    Gene ID
    3718
    HGNC
    3718
    Pathways
    JAK-STAT Signaling, RTK Signaling, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response
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