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JAK3 antibody (pTyr785)

JAK3 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7250815
  • Target See all JAK3 Antibodies
    JAK3 (Janus Kinase 3 (JAK3))
    Binding Specificity
    • 16
    • 13
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr785
    Reactivity
    • 88
    • 49
    • 18
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 84
    • 6
    Rabbit
    Clonality
    • 69
    • 21
    Polyclonal
    Conjugate
    • 33
    • 8
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This JAK3 antibody is un-conjugated
    Application
    • 50
    • 28
    • 23
    • 14
    • 14
    • 11
    • 8
    • 7
    • 6
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Characteristics
    Phosphorylated antibody
    Purification
    Affinity purification
    Immunogen
    Synthesized peptide derived from human JAK3 around the phosphorylation site of Tyr785
    Isotype
    IgG
    Top Product
    Discover our top product JAK3 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    JAK3 (Janus Kinase 3 (JAK3))
    Alternative Name
    JAK3 (JAK3 Products)
    Synonyms
    JAK-3 antibody, JAK3_HUMAN antibody, JAKL antibody, L-JAK antibody, LJAK antibody, fae antibody, wil antibody, RATJAK3 antibody, JAK antibody, Janus kinase 3 antibody, JAK3 antibody, Jak3 antibody
    Background
    The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
    Molecular Weight

    Observed_MW: 125 kDa

    Calculated_MW: 125 kDa

    UniProt
    P52333
    Pathways
    JAK-STAT Signaling, RTK Signaling, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response
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