Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1) (full length) antibody

Details for Product No. ABIN561369
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Antigen
Synonyms 11-DH, 11-beta-HSD1, CORTRD2, HDL, HSD11, HSD11B, HSD11L, SDR26C1, hsd11, hsd11b, LRRGT00065
Epitope
full length
(19), (14), (13), (6), (3), (2)
Reactivity
Human
(66), (13), (12), (7), (1), (1), (1), (1)
Host
Mouse
(37), (15), (15)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(5), (5), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
(49), (32), (13), (10), (7), (7), (7), (6), (3), (2), (1)
Pubmed 5 references available
Quantity 100 μg
Shipping to United States (Change)
Availability Will be delivered in 11 to 12 Business Days
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Catalog No. ABIN561369
330.00 $
Plus shipping costs $45.00 and $22.00 dry ice

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Immunogen HSD3B1 (AAH31999.1, 1 a.a. ~ 373 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 kDa.
Immunogen sequence: MTGWSCLVTG AGGFLGQRII RLLVKEKELK EIRVLDKAFG PELREEFSKL QNKTKLTVLE GDILDEPFLK RACQDVSVII HTACIIDVFG VTHRESIMNV NVKGTQLLLE ACVQASVPVF IYTSSIEVAG PNSYKEIIQN GHEEEPLENT WPAPYPHSKK LAEKAVLAAN GWNLKNGGTL YTCALRPMYI YGEGSRFLSA SINEALNNNG ILSSVGKFST VNPVYVGNVA WAHILALRAL QDPKKAPSIR GQFYYISDDT PHQSYDNLNY TLSKEFGLRL DSRWSFPLSL MYWIGFLLEI VSFLLRPIYT YRPPFNRHIV TLSNSVFTFS YKKAQRDLAY KPLYSWEEAK QKTVEWVGSL VDRHKENLKS KTQ
Clone 3C11-D4
Isotype IgG1 kappa
Alternative Name HSD3B1
Background Gene: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
Synonyms: HSD3B, HSDB3, SDR11E1
Gene ID 3283
Research Area Cancer, Hormones
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Buffer In 1x PBS, pH 7.4
Handling Advice Aliquot to avoid repeated freezing and thawing.
Storage -20
Storage Comment Store at -20
Supplier Images
anti-Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1) (full length) antibody Immunoperoxidase of monoclonal antibody to HSD3B1 on formalin-fixed paraffin-embedded human placenta. (antibody concentration 3 ᄉg/mL)
anti-Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1) (full length) antibody (2) HSD3B1 monoclonal antibody (M01), clone 3C11-D4. Western Blot analysis of HSD3B1 expression in human placenta.
anti-Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1) (full length) antibody (3) Immunohistochemical staining of various tissues with hematoxylin and HSD3B1 antibody under high magnification.(antibody concentration 3 ᄉg/mL)
( a ) Stomach
( b ) Esophagus
( c ) Endometrium
( d ) Uterine cervix
( e ) Placenta
( f ) Ovary, clear cell carcinoma
( g ) Hepatocellular carcinoma
( h ) Breast cancer
( i ) Colon adenocarcinoma
( j and k ) Cervical carcinoma
( l, m, and n ) Choriocarcinoma
( o ) Epithelioid trophoblastic tumor.
anti-Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1) (full length) antibody (4) Western Blot analysis of HSD3B1 expression in transfected 293T cell line by HSD3B1 monoclonal antibody (M01), clone 3C11-D4.

Lane 1: HSD3B1 transfected lysate (Predicted MW: 42.3 KDa).
Lane 2: Non-transfected lysate.
anti-Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1) (full length) antibody (5) Western Blot detection against Immunogen (66.77 KDa) .
Product cited in: Azmahani, Nakamura, Felizola et al.: "Steroidogenic enzymes, their related transcription factors and nuclear receptors in human sebaceous glands under normal and pathological conditions." in: The Journal of steroid biochemistry and molecular biology, Vol. 144 Pt B, pp. 268-79, 2014 (PubMed).

Mao, Shih: "Advances in the diagnosis of gestational trophoblastic tumors and tumor-like lesions." in: Expert opinion on medical diagnostics, Vol. 3, Issue 4, pp. 371-80, 2013 (PubMed).

Background publications Ariel, Boldes, Weintraub et al.: "Chorangiocarcinoma: a case report and review of the literature." in: International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, Vol. 28, Issue 3, pp. 267-71, 2009 (PubMed).

Mao, Kurman, Jeng et al.: "HSD3B1 as a novel trophoblast-associated marker that assists in the differential diagnosis of trophoblastic tumors and tumorlike lesions." in: The American journal of surgical pathology, Vol. 32, Issue 2, pp. 236-42, 2008 (PubMed).

Shih: "Trophogram, an immunohistochemistry-based algorithmic approach, in the differential diagnosis of trophoblastic tumors and tumorlike lesions." in: Annals of diagnostic pathology, Vol. 11, Issue 3, pp. 228-34, 2007 (PubMed).

Validation Images
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