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HSD3B1 Products

(Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1))

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3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.

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Featured HSD3B1 Categories

HSD3B1 Antibodies

High quality antibodies with extensive validation data.

HSD3B1 ELISA Kits

Reliable ELISA kits for a wide range of species.

HSD3B1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HSD3B1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (6)
  • (5)
Cat. No. ABIN561369
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (5)
Cat. No. ABIN516698
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN6142016
Quantity 100 μL
Datasheet Datasheet

Recommended HSD3B1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967488
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
Cat. No. ABIN6967487
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6225342
Quantity 96 tests
Datasheet Datasheet

Recommended HSD3B1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307142
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3112907
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3133419
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our HSD3B1 products

Chen, Guo, Xiao, Ye, Huang, Lu, Su: "Identification and functional characterization of microRNAs in rat Leydig cells during development from the progenitor to the adult stage." in: Molecular and cellular endocrinology, Vol. 493, pp. 110453, (2019) (PubMed).

An, Zhang, Liu, Zhou, Yang, Wang: "MiR-1197-3p regulates testosterone secretion in goat Leydig cells via targeting PPARGC1A." in: Gene, Vol. 710, pp. 131-139, (2019) (PubMed).

Mirkheshti, Park, Jiang, Cropper, Werner, Song, Chatterjee: "Dual targeting of androgen receptor and mTORC1 by salinomycin in prostate cancer." in: Oncotarget, Vol. 7, Issue 38, pp. 62240-62254, (2016) (PubMed).

Kubota-Nakayama, Nakamura, Konosu-Fukaya, Azmahani, Ise, Yamazaki, Kitawaki, Felizola, Ono, Omata, Morimoto, Iwama, Satoh, Sasano et al.: "Expression of steroidogenic enzymes and their transcription factors in cortisol-producing adrenocortical adenomas: immunohistochemical analysis and quantitative real-time polymerase chain reaction ..." in: Human pathology, Vol. 54, pp. 165-73, (2016) (PubMed).

Azmahani, Nakamura, Felizola, Ozawa, Ise, Inoue, McNamara, Doi, Okamura, Zouboulis, Aiba, Sasano: "Steroidogenic enzymes, their related transcription factors and nuclear receptors in human sebaceous glands under normal and pathological conditions." in: The Journal of steroid biochemistry and molecular biology, Vol. 144 Pt B, pp. 268-79, (2014) (PubMed).

Mao, Shih: "Advances in the diagnosis of gestational trophoblastic tumors and tumor-like lesions." in: Expert opinion on medical diagnostics, Vol. 3, Issue 4, pp. 371-80, (2013) (PubMed).

Palaniappan, Menon: "Luteinizing hormone/human chorionic gonadotropin-mediated activation of mTORC1 signaling is required for androgen synthesis by theca-interstitial cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 26, Issue 10, pp. 1732-42, (2012) (PubMed).

Ariel, Boldes, Weintraub, Reinus, Beller, Arbel: "Chorangiocarcinoma: a case report and review of the literature." in: International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, Vol. 28, Issue 3, pp. 267-71, (2009) (PubMed).

Mao, Kurman, Jeng, Huang, Shih: "HSD3B1 as a novel trophoblast-associated marker that assists in the differential diagnosis of trophoblastic tumors and tumorlike lesions." in: The American journal of surgical pathology, Vol. 32, Issue 2, pp. 236-42, (2008) (PubMed).

Shih: "Trophogram, an immunohistochemistry-based algorithmic approach, in the differential diagnosis of trophoblastic tumors and tumorlike lesions." in: Annals of diagnostic pathology, Vol. 11, Issue 3, pp. 228-34, (2007) (PubMed).

Synonyms and alternative names related to HSD3B1

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 (HSD3B1), 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (LOC469446), 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (LOC713091), hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 L homeolog (hsd3b1.L), 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (LOC100451655), hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 (Hsd3b1), hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 (hsd3b1), 3B-HSD, 3BETAHSD, 3BHSD, D3Ertd383e, HSD3B, HSD3B1, HSDB3, HSDB3A, I, MGC131206, SDR11E1, si:rp71-68n21.10

Protein level used designations for HSD3B1

  • 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1
  • 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I
  • 3-beta-HSD I
  • 3-beta-hydroxy-5-ene steroid dehydrogenase
  • 3-beta-hydroxy-Delta(5)-steroid dehydrogenase
  • delta-5-3-ketosteroid isomerase
  • hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 1
  • progesterone reductase
  • short chain dehydrogenase/reductase family 11E, member 1
  • steroid Delta-isomerase
  • trophoblast antigen FDO161G
  • hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
  • 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1-like
  • hydroxysteroid dehydrogenase-1, delta<5>-3-beta
  • 3 beta-hydroxysteroid dehydrogenase 1
  • 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase
  • 3-beta-HSD
  • 3-beta-hydroxysteroid dehydrogenase/delta-5-delta-4 isomerase
  • hydroxy-delta-MAY-steroid dehydrogenase, 3 beta- and steroid delta-isomerase
  • 3beta-hydroxysteroid dehydrogenase/isomerase
  • LOW QUALITY PROTEIN: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1
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