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CD11b antibody (PE)

ITGAM Reactivity: Rat FACS Host: Mouse Monoclonal PE
Catalog No. ABIN576554
  • Target See all CD11b (ITGAM) Antibodies
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Reactivity
    • 248
    • 155
    • 62
    • 33
    • 17
    • 17
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    • 14
    • 11
    • 7
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    • 5
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    • 1
    Rat
    Host
    • 133
    • 99
    • 94
    • 2
    • 1
    • 1
    Mouse
    Clonality
    • 234
    • 92
    • 1
    Monoclonal
    Conjugate
    • 107
    • 36
    • 29
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This CD11b antibody is conjugated to PE
    Application
    • 248
    • 78
    • 74
    • 70
    • 55
    • 36
    • 36
    • 22
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    • 13
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    Flow Cytometry (FACS)
    Specificity
    Recognizes a membrane antigen on rat macrophages, monocytes, dendritic cells and granulocytes. Recognizes small ramified microglia in the central nervous system. No other cell types are positive for ED8. The recognized antigen is a heterodimer (160 and 95kD) belonging to the family of adhesion molecules CD11b/CD18, also designated as Mac-1 antigen or CR3. ED7 and ED8 recognize different epitopes on the same molecule.
    Purification
    Ion exchange chromatography
    Immunogen
    Rat spleen cell homogenate.
    Isotype
    IgG1
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  • Application Notes
    Approved: Flo (1:1)

    Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
    Comment

    Target Species of Antibody: Rat

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Distilled Water.
    Concentration
    Lot specific
    Buffer
    Lyophilized, PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Target
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Alternative Name
    ITGAM / CD11b (ITGAM Products)
    Synonyms
    CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody
    Background
    Name/Gene ID: ITGAM
    Family: Integrin

    Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain
    Gene ID
    3684
    Pathways
    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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