SPTLC1 antibody (Middle Region)
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- Target See all SPTLC1 Antibodies
- SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SPTLC1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- SPTLC1 antibody was raised against the middle region of SPTLC1
- Purification
- Affinity purified
- Immunogen
- SPTLC1 antibody was raised using the middle region of SPTLC1 corresponding to a region with amino acids DLERLLKEQEIEDQKNPRKARVTRRFIVVEGLYMNTGTICPLPELVKLKY
- Top Product
- Discover our top product SPTLC1 Primary Antibody
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- Application Notes
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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SPTLC1 Blocking Peptide, catalog no. 33R-2041, is also available for use as a blocking control in assays to test for specificity of this SPTLC1 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SPTLC1 antibody in PBS
- Concentration
- Lot specific
- Buffer
- PBS
- Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Target
- SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
- Alternative Name
- SPTLC1 (SPTLC1 Products)
- Synonyms
- ATSPT1 antibody, SERINE PALMITOYLTRANSFERASE 1 antibody, serine palmitoyltransferase 1 antibody, Afu6g00300 antibody, HSAN1 antibody, HSN1 antibody, LBC1 antibody, LCB1 antibody, SPT1 antibody, SPTI antibody, wu:fc75h04 antibody, wu:fp41c08 antibody, zgc:112247 antibody, AW552086 antibody, C77762 antibody, E030036H05 antibody, Lcb1 antibody, RGD1306617 antibody, Spt1 antibody, serine palmitoyltransferase 1 antibody, Serine palmitoyltransferase 1 antibody, serine palmitoyltransferase long chain base subunit 1 antibody, serine palmitoyltransferase, long chain base subunit 1 antibody, serine palmitoyltransferase, long chain base subunit 1 L homeolog antibody, SPT1 antibody, AFUA_6G00300 antibody, PAS_FragB_0040 antibody, SPTLC1 antibody, sptlc1 antibody, sptlc1.L antibody, Sptlc1 antibody
- Background
- Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. SPTLC1 is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in SPTLC1 gene were identified in patients with hereditary sensory neuropathy type 1.
- Molecular Weight
- 53 kDa (MW of target protein)
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