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TNF alpha antibody
TNF alpha
Reactivity: Mouse
ELISA, FACS, IHC (fro)
Host: Rat
unconjugated
Product Details anti-TNF alpha Antibody
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Target
See all TNF alpha Antibodies
TNF alpha
(Tumor Necrosis Factor alpha (TNF alpha))
Reactivity
All reactivities for TNF alpha antibodies
Mouse
Host
All hosts for TNF alpha antibodies
Rat
Conjugate
All conjugates for TNF alpha antibodies
This TNF alpha antibody is un-conjugated
Application
All applications for TNF alpha antibodies
ELISA, Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
Specificity
DS-MB-02427 is specific for mouse tumor necrosis factor alpha (TNF alpha), a 17 KDa cytokine produced by monocytes, macrophages, neutrophils, NK cells and CD4+ T cells. TNF alpha forms dimers and trimers, and is also found as a 26KDa integral membrane protein. Mouse TNF alpha has cytolytic activity against many tumor cell lines, and has an important immuno-regulatory role. DS-MB-02427 is reported to neutralize the effects of mouse TNF alpha (4,5).
Cross-Reactivity
Rat (Rattus)
Characteristics
Rat Anti-Mouse Tumor Necrosis Factor alpha (TNF-alpha)
Purification
Purified
Immunogen
Recombinant murine TNF alpha expressed in E. coli
Isotype
IgG1
Top Product
Discover our top product TNF alpha Primary Antibody
Alternatives
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Application Details
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Restrictions
For Research Use only
Handling
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Concentration
IgG concentration 1.0 mg/ml
Buffer
Phosphate buffered saline
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Target Details for TNF alpha
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Target
TNF alpha
(Tumor Necrosis Factor alpha (TNF alpha))
Alternative Name
Tumor Necrosis Factor alpha (TNF-alpha) (TNF alpha Products )
Synonyms
DIF antibody, TNF-alpha antibody, TNFA antibody, TNFSF2 antibody, RATTNF antibody, Tnfa antibody, tnf antibody, TNF-a antibody, TNFalpha antibody, Tnfsf1a antibody, TNFa antibody, cTNF antibody, Tnf-alpha antibody, tnfa-like antibody, TNF-ALPHA antibody, dif antibody, tnfa antibody, xtnf antibody, tnfsf2 antibody, tnf-alpha antibody, Cachectin antibody, tumor necrosis factor antibody, tumor necrosis factor b (TNF superfamily, member 2) antibody, tumor necrosis factor alpha antibody, tumor necrosis factor a (TNF superfamily, member 2) antibody, TNF antibody, Tnf antibody, tnf antibody, tnfb antibody, tnf-alpha antibody, LOC103694380 antibody, tnfa antibody
Pathways
NF-kappaB Signaling , Apoptosis , Caspase Cascade in Apoptosis , TLR Signaling , Cellular Response to Molecule of Bacterial Origin , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Production of Molecular Mediator of Immune Response , Positive Regulation of Endopeptidase Activity , Hepatitis C , Protein targeting to Nucleus , Inflammasome
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