Kallikrein 6 antibody (KLK6) (AA 1-30)

Details for Product anti-KLK6 Antibody No. ABIN652195, Supplier: Log in to see
Antigen
  • klk6
  • KLK8
  • Klk1b21
  • Klk6
  • rGK-8
  • rk8
  • AI849898
  • BSP
  • Bssp
  • Klk29
  • MSP
  • Prss18
  • Prss9
  • neurosin
  • Klk7
  • PRSS18
  • PRSS9
  • SP59
  • hK6
  • kallikrein 6
  • kallikrein 1-related peptidase C8
  • kallikrein related-peptidase 6
  • kallikrein-related peptidase 6
  • klk6
  • Klk1c8
  • Klk6
  • KLK6
Alternatives
anti-Human Kallikrein 6 antibody for Cellular Assay
Epitope
AA 1-30, N-Term
17
15
9
6
5
5
5
4
4
3
3
2
2
1
1
1
1
1
1
1
Reactivity
Human
70
29
28
4
2
1
1
Host
Rabbit
66
23
10
Clonality (Clone)
Polyclonal ()
Conjugate
This Kallikrein 6 antibody is un-conjugated
7
5
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
70
49
20
13
13
8
6
3
3
2
2
2
1
1
1
1
Options
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Immunogen This Kallikrein 6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human Kallikrein 6.
Clone RB6114
Isotype Ig
Specificity This Kallikrein 6 Antibody antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6~35 amino acids from the N-terminal region of human KLK6.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Background Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The KLK6 enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.
Synonyms: Protease M, Neurosin, Zyme, SP59,
Molecular Weight 26856 DA
Gene ID 5653
UniProt Q92876
Research Area Neurology, Cell Structure
Pathways Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling
Application Notes WB = 1:1000, IHC (p) = 1:10-50, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Kallikrein 6 antibody (KLK6) (AA 1-30) (ABIN652195) Western blot analysis of KLK6 (arrow) using rabbit polyclonal KLK6 Antibody (A13) (AB...
Immunohistochemistry (IHC) image for anti-Kallikrein 6 antibody (KLK6) (AA 1-30) (ABIN652195) Kallikrein 6(KLK6) Antibody (N-term) (ABIN652195)immunohistochemistry analysis in for...
Background publications Pampalakis, Kurlender, Diamandis, Sotiropoulou: "Cloning and characterization of novel isoforms of the human kallikrein 6 gene." in: Biochemical and biophysical research communications, Vol. 320, Issue 1, pp. 54-61, 2004 (PubMed).

Ghosh, Grass, Soosaipillai, Sotiropoulou, Diamandis: "Human kallikrein 6 degrades extracellular matrix proteins and may enhance the metastatic potential of tumour cells." in: Tumour biology, Vol. 25, Issue 4, pp. 193-9, 2004 (PubMed).

Sauter, Lininger, Magklara, Hewett, Diamandis: "Association of kallikrein expression in nipple aspirate fluid with breast cancer risk." in: International journal of cancer. Journal international du cancer, Vol. 108, Issue 4, pp. 588-91, 2003 (PubMed).