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Details for Product No. ABIN659026

V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3) antibody

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Antigen
Synonyms AI851531, D930002M15Rik, Nmf350, Pkbg, MPPH, PKB-GAMMA, PKBG, PRKBG, RAC-PK-gamma, RAC-gamma, STK-2
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN659026
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This AKT3 monoclonal antibody is generated from mouse immunized with AKT3 recombinant protein.
Clone 154CT4-5-3
Isotype Ig
Specificity This AKT3 monoclonal antibody is generated from mouse immunized with AKT3 recombinant protein.
Purification This antibody is purified through a protein G column, followed by dialysis against PBS.
Alternative Name AKT3
Background AKT3 is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1).
Synonyms: STK-2, Protein kinase B gamma, PKB gamma, Protein kinase Akt-3, RAC-PK-gamma, RAC-gamma serine/threonine-protein kinase,PKBG, AKT3
Molecular Weight 55775 DA
Gene ID 10000
UniProt Q9Y243, NP_859029.1
Research Area Ubiquitin-related antibodies, Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications, Chromatin, Signaling
Application Notes Recommend dilutions: WB : 1:100-500,IHC : 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.32 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Yang, Wang, Chan et al.: "The E3 ligase TRAF6 regulates Akt ubiquitination and activation." in: Science (New York, N.Y.), Vol. 325, Issue 5944, pp. 1134-8, 2009 (PubMed).

Alternatives for antigen "V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3)", type "Antibodies"
Hosts (88), (42), (10), (3)
Reactivities (142), (70), (58), (37), (34), (20), (17), (1), (1), (1)
Applications (107), (70), (31), (29), (20), (17), (5), (4), (4), (2), (2), (1), (1), (1), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (21), (15), (8), (8), (6), (4), (4), (3), (2), (1), (1), (1), (1)
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