GTPase NRas antibody

Catalog No. ABIN781534

The Mouse Monoclonal anti-GTPase NRas antibody (Clone AT2G9) (ABIN781534) specifically detects GTPase NRas in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for GTPase NRas antibody (ABIN781534)

Target: GTPase NRas (NRAS)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GTPase NRas antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT2G9

Product Details anti-GTPase NRas Antibody

Specificity: The antibody recognizes human RAS. Other species not tested.

Purification: Protein-G affinity chromatography

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for GTPase NRas

Target: GTPase NRas (NRAS)

Alternative Name: NRAS

Background: The Ras protein is a subfamily of small GTPases that are involved in signal transduction. They are activated by ligand-binding receptor tyrosine kinases such as EGFR, PDGFR, CSF and FGF. These kinases transiently convert RAS-GDP (inactive form) to RAS-GTP, the active form of RAS. The main genes are HRAS, NRAS and KRAS.Synonyms: HRAS, HRAS1, KRAS, KRAS2, NRAS, RASK2

Gene ID: 4893

Pathways: p53 Signaling, MAPK Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling