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ROCK1 antibody (N-Term)
ROCK1
Reactivity: Human, Mouse, Rat
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ROCK1 Antibody
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Target
See all ROCK1 Antibodies
ROCK1
(rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))
Binding Specificity
All epitopes for ROCK1 antibodies
N-Term
Reactivity
All reactivities for ROCK1 antibodies
Human, Mouse, Rat
Host
All hosts for ROCK1 antibodies
Rabbit
Clonality
All clonalities for ROCK1 antibodies
Polyclonal
Conjugate
All conjugates for ROCK1 antibodies
This ROCK1 antibody is un-conjugated
Application
All applications for ROCK1 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody detects ROCK1 at N-term. ROCK1 antibody is predicted to not cross-react with other ROCK protein family members.
Cross-Reactivity (Details)
Species reactivity (tested):Human, mouse, rat
Purification
Affinity chromatography purified via peptide column
Immunogen
15 amino acid peptide near the amino terminus of human ROCK1
Top Product
Discover our top product ROCK1 Primary Antibody
Alternatives
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anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (pSer456), (pThr455) antibody
ROCK1
Reactivity: Human, Mouse, Rat
WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
PBS containing 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Target Details for ROCK1
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Target
ROCK1
(rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))
Alternative Name
ROCK1 (ROCK1 Products )
Synonyms
LOC100229794 antibody, CG9774 antibody, DROK antibody, DRhk antibody, DRok antibody, Dmel\\CG9774 antibody, Drok antibody, ROCK antibody, ROCK-1 antibody, ROCK1 antibody, ROK antibody, ROKalpha/beta antibody, Rhk antibody, RhoK antibody, Rock antibody, Rok antibody, dROK antibody, dRok antibody, drok antibody, 1110055K06Rik antibody, Rock-I antibody, P160Rock antibody, ROCK-I antibody, P160ROCK antibody, p160ROCK antibody, Rho associated coiled-coil containing protein kinase 1 antibody, Rho kinase antibody, Rho-associated coiled-coil containing protein kinase 1 antibody, Rho-associated, coiled-coil containing protein kinase 1 antibody, ROCK1 antibody, Rok antibody, Rock1 antibody, rock1 antibody
Background
ROCK1 is a member of the AGC serine/threonine protein kinase family that regulates the assembly of the actin cytoskeleton. ROCK1 contains a protein kinase domain, a coiled-coil region and a zinc finger region and appears to be present as a dimer. ROCK1, like its isozyme ROCK2, is a downstream target of the small G-protein Rho and plays a role in smooth muscle contraction, malignant cell transformation, tumor invasion and metastasis, and mediates the cellular morphological changes during apoptosis.Synonyms: NY-REN-35, ROCK-1, Renal carcinoma antigen NY-REN-35, Rho-associated, Rho-associated protein kinase 1, coiled-coil-containing protein kinase 1, p160ROCK
Gene ID
6093
NCBI Accession
NP_005397
UniProt
Q13464
Pathways
Microtubule Dynamics , WNT Signaling , M Phase , Maintenance of Protein Location , Signaling Events mediated by VEGFR1 and VEGFR2 , Thromboxane A2 Receptor Signaling
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