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NLRP6 antibody (N-Term)
NLRP6
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NLRP6 Antibody
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Target
See all NLRP6 Antibodies
NLRP6
(NLR Family, Pyrin Domain Containing 6 (NLRP6))
Binding Specificity
All epitopes for NLRP6 antibodies
N-Term
Reactivity
All reactivities for NLRP6 antibodies
Human
Host
All hosts for NLRP6 antibodies
Rabbit
Clonality
All clonalities for NLRP6 antibodies
Polyclonal
Conjugate
All conjugates for NLRP6 antibodies
This NLRP6 antibody is un-conjugated
Application
All applications for NLRP6 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody detects NLRP6 at N-term.
Cross-Reactivity (Details)
Species reactivity (tested):Human
Purification
Affinity chromatography purified via peptide column
Immunogen
16 amino acid peptide near the amino terminus of human NALP6
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Discover our top product NLRP6 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
PBS containing 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Target Details for NLRP6
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Target
NLRP6
(NLR Family, Pyrin Domain Containing 6 (NLRP6))
Alternative Name
NLRP6 (NLRP6 Products )
Synonyms
NLRP6 antibody, NALP6 antibody, AVR antibody, CLR11.4 antibody, NAVR antibody, NAVR/AVR antibody, PAN3 antibody, PYPAF5 antibody, AI504961 antibody, Avr antibody, Nalp6 antibody, Navr antibody, Navr/Avr antibody, Pypaf5 antibody, NLR family pyrin domain containing 6 antibody, NLR family, pyrin domain containing 6 antibody, NLRP6 antibody, Nlrp6 antibody
Background
NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP6, also known as PYPAF5, is highly expressed in granulocytes and T cells and co-localizes with the PYRIN-CARD protein ASC. Co-expression of NALP6 with ASC results in a synergistic activation of NF-kB and activated caspase-1-dependent cytokine processing, suggesting that NALP6 functions in immune cells to coordinate the transduction of pro-inflammatory signals.Synonyms: LRR and PYD domains-containing protein 6, NACHT, NALP6, PYPAF5
Gene ID
171389
NCBI Accession
NP_612202
UniProt
P59044
Pathways
Inflammasome
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