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TLR3 antibody

TLR3 Reactivity: Human, Mouse, Rat WB Host: Goat Polyclonal unconjugated
Catalog No. ABIN783847
  • Target See all TLR3 Antibodies
    TLR3 (Toll-Like Receptor 3 (TLR3))
    Reactivity
    • 96
    • 64
    • 30
    • 6
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 86
    • 29
    • 3
    • 1
    Goat
    Clonality
    • 88
    • 31
    Polyclonal
    Conjugate
    • 51
    • 18
    • 15
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLR3 antibody is un-conjugated
    Application
    • 82
    • 41
    • 38
    • 35
    • 23
    • 16
    • 13
    • 13
    • 13
    • 13
    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Specificity
    This antibody detects ~103 kDa of TLR3.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Affinity chromatography
    Immunogen
    Synthetic peptide surrounding amino acid 805 of mouse TLR3
    Top Product
    Discover our top product TLR3 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2, containing 30 % clycerol, 0.5 % BSA, and 0.1 %thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Upon receipt, store at -20 °C. For long term storage, aliquot and store at -70 °C.
  • Target
    TLR3 (Toll-Like Receptor 3 (TLR3))
    Alternative Name
    CD283 / TLR3 (TLR3 Products)
    Synonyms
    CD283 antibody, IIAE2 antibody, AI957183 antibody, zgc:123006 antibody, toll like receptor 3 antibody, toll-like receptor 3 antibody, TLR3 antibody, Tlr3 antibody, tlr3 antibody
    Background
    To date, at least ten members of the Toll family have been identified. TLRs recognize molecular patterns associated with microbial pathogens and induce antimicrobial immune response. TLR3 recognizes double-stranded (ds) RNA, induces the activation of NF-kB, through MyD88-dependent and -independent pathways, and the production of type I interferons (IFNs). Similar to several other members of the TLR family, TLR3 has been reported to be expressed at a very low level on the surface of human fibroblast cell lines.Synonyms: Toll-like receptor 3
    Gene ID
    7098
    NCBI Accession
    NP_003256
    UniProt
    O15455
    Pathways
    TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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