TLR3 antibody
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- Target See all TLR3 Antibodies
- TLR3 (Toll-Like Receptor 3 (TLR3))
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Reactivity
- Human, Mouse, Rat
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This TLR3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- This antibody detects ~103 kDa of TLR3.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human, mouse, rat
- Purification
- Affinity chromatography
- Immunogen
- Synthetic peptide surrounding amino acid 805 of mouse TLR3
- Top Product
- Discover our top product TLR3 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2, containing 30 % clycerol, 0.5 % BSA, and 0.1 %thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Upon receipt, store at -20 °C. For long term storage, aliquot and store at -70 °C.
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- Target
- TLR3 (Toll-Like Receptor 3 (TLR3))
- Alternative Name
- CD283 / TLR3 (TLR3 Products)
- Synonyms
- CD283 antibody, IIAE2 antibody, AI957183 antibody, zgc:123006 antibody, toll like receptor 3 antibody, toll-like receptor 3 antibody, TLR3 antibody, Tlr3 antibody, tlr3 antibody
- Background
- To date, at least ten members of the Toll family have been identified. TLRs recognize molecular patterns associated with microbial pathogens and induce antimicrobial immune response. TLR3 recognizes double-stranded (ds) RNA, induces the activation of NF-kB, through MyD88-dependent and -independent pathways, and the production of type I interferons (IFNs). Similar to several other members of the TLR family, TLR3 has been reported to be expressed at a very low level on the surface of human fibroblast cell lines.Synonyms: Toll-like receptor 3
- Gene ID
- 7098
- NCBI Accession
- NP_003256
- UniProt
- O15455
- Pathways
- TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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