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Aurora A antibody
AURKA
Reactivity: Human, Rat, Monkey
WB, ELISA, IHC, FACS
Host: Mouse
Monoclonal
1F8
unconjugated
Product Details anti-Aurora A Antibody
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Target
See all Aurora A (AURKA) Antibodies
Aurora A (AURKA)
(Aurora Kinase A (AURKA))
Reactivity
All reactivities for Aurora A antibodies
Human, Rat, Monkey
Host
All hosts for Aurora A antibodies
Mouse
Clonality
All clonalities for Aurora A antibodies
Monoclonal
Conjugate
All conjugates for Aurora A antibodies
This Aurora A antibody is un-conjugated
Application
All applications for Aurora A antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
Purification
Ascitic fluid
Immunogen
Purified recombinant fragment of human AURKA expressed in E. Coli.
Clone
1F8
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
WB: 1/500 - 1/2000, IHC: 1/200-1/1000, FC: 1/200-1/400, ELISA: Propose dilution 1/10000.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
100g/100l
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Target Details for Aurora A
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Target
Aurora A (AURKA)
(Aurora Kinase A (AURKA))
Alternative Name
AURKA (AURKA Products )
Synonyms
AIK antibody, ARK1 antibody, AURA antibody, AURORA2 antibody, BTAK antibody, PPP1R47 antibody, STK15 antibody, STK6 antibody, STK7 antibody, AIRK1 antibody, AU019385 antibody, AW539821 antibody, Ark1 antibody, Aurora-A antibody, Ayk1 antibody, IAK antibody, IAK1 antibody, Stk6 antibody, 87A7-9/2 antibody, Aur-A antibody, AurA antibody, CG3068 antibody, Dmel\\CG3068 antibody, aur-A antibody, aurA antibody, ck10 antibody, ck[10] antibody, l(3)87Ac antibody, l(3)ck10 antibody, ARK-1 antibody, Eg2 antibody, aik antibody, ark1 antibody, aur-a antibody, aura antibody, aurka-a antibody, aurora2 antibody, btak antibody, stk15 antibody, stk6 antibody, stk7 antibody, pEg2 antibody, wu:fb37c10 antibody, wu:fc02c02 antibody, zgc:100912 antibody, AURKA antibody, aurka antibody, aurora kinase A antibody, aurora A antibody, aurora kinase A L homeolog antibody, hypothetical protein antibody, aurora kinase A S homeolog antibody, AURKA antibody, Aurka antibody, aurA antibody, aurka.L antibody, aurka antibody, Aurora-A antibody, aurka.S antibody
Background
Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment. Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines. Synonyms: AIK, ARK1, AURA, BTAK, STK6, STK7, STK15, AURORA2, MGC34538, AURKA
Molecular Weight
48kDa
Gene ID
6790
Pathways
Cell Division Cycle , Asymmetric Protein Localization
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