TNFRSF4 antibody (Middle Region)
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- Target See all TNFRSF4 Antibodies
- TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
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Binding Specificity
- Middle Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TNFRSF4 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Purified
- Immunogen
- TNFRSF4 antibody was raised in rabbit using the middle region of TNFRSF4 as the immunogen
- Top Product
- Discover our top product TNFRSF4 Primary Antibody
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- Application Notes
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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TNFRSF4 Blocking Peptide, catalog no. 33R-3362, is also available for use as a blocking control in assays to test for specificity of this TNFRSF4 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Target
- TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
- Alternative Name
- TNFRSF4 (TNFRSF4 Products)
- Synonyms
- TNFRSF4 antibody, ACT35 antibody, CD134 antibody, Ly-70 antibody, Ox40 antibody, TXGP1L antibody, Txgp1 antibody, OX40 antibody, TNF receptor superfamily member 4 antibody, tumor necrosis factor receptor superfamily, member 4 antibody, TNFRSF4 antibody, Tnfrsf4 antibody
- Background
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. Synonyms: Polyclonal TNFRSF4 antibody, Anti-TNFRSF4 antibody, tumor necrosis factor receptor superfamily, member 4 antibody, ACT35 antibody, CD134 antibody, OX40 antibody, TXGP1L antibody.
- Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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