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Estrogen Receptor alpha antibody (AA 53-301)
ESR1
Reactivity: Human, Mouse
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Estrogen Receptor alpha Antibody
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Target
See all Estrogen Receptor alpha (ESR1) Antibodies
Estrogen Receptor alpha (ESR1)
(Estrogen Receptor 1 (ESR1))
Binding Specificity
All epitopes for Estrogen Receptor alpha antibodies
AA 53-301
Reactivity
All reactivities for Estrogen Receptor alpha antibodies
Human, Mouse
Host
All hosts for Estrogen Receptor alpha antibodies
Rabbit
Clonality
All clonalities for Estrogen Receptor alpha antibodies
Polyclonal
Conjugate
All conjugates for Estrogen Receptor alpha antibodies
This Estrogen Receptor alpha antibody is un-conjugated
Application
All applications for Estrogen Receptor alpha antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes Human and Mouse Estrogen receptor alpha.
Purification
Affinity Chromatography on Protein A
Immunogen
Recombinant protein between 53-301 amino acids from Human Estrogen receptor alpha. Genename: ESR1
Isotype
Ig Fraction
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Discover our top product ESR1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for Estrogen Receptor alpha
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Target
Estrogen Receptor alpha (ESR1)
(Estrogen Receptor 1 (ESR1))
Alternative Name
Estrogen Receptor alpha (ESR1 Products )
Synonyms
LOC398734 antibody, AA420328 antibody, AU041214 antibody, ER-alpha antibody, ER[a] antibody, ERa antibody, ERalpha antibody, ESR antibody, Estr antibody, Estra antibody, Nr3a1 antibody, NR3A1 antibody, eralpha antibody, zfER[a] antibody, ER antibody, ESRA antibody, ESTRR antibody, Era antibody, akap12 antibody, cb27 antibody, esr1 antibody, fb72g12 antibody, id:ibd1202 antibody, sb:cb27 antibody, si:ch73-192g21.1 antibody, wu:fb72g12 antibody, wu:fc21c03 antibody, Esr antibody, RNESTROR antibody, ERALPHA antibody, er antibody, esr antibody, nr3a1 antibody, XER antibody, era antibody, esra antibody, ERbeta antibody, xesr-1 antibody, xlERalpha1 antibody, xlERalpha2 antibody, ESR1 antibody, estrogen receptor 1 L homeolog antibody, estrogen receptor 1 (alpha) antibody, estrogen receptor 1 antibody, A kinase (PRKA) anchor protein 12b antibody, esr1.L antibody, Esr1 antibody, ESR1 antibody, esr1 antibody, akap12b antibody
Background
ESR1 is an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.Synonyms: ER alpha, ESR, ESR1, Estradiol receptor, NR3A1, Nuclear receptor subfamily 3 group A member 1
Molecular Weight
66216 Da
Gene ID
2099
NCBI Accession
NP_001116213
Pathways
Nuclear Receptor Transcription Pathway , EGFR Signaling Pathway , Retinoic Acid Receptor Signaling Pathway , Intracellular Steroid Hormone Receptor Signaling Pathway , Steroid Hormone Mediated Signaling Pathway , Ribonucleoprotein Complex Subunit Organization , Ribosome Assembly
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