×
For best experience we recommend to activate Javascript in your browser.
GAD65 antibody (Middle Region)
GAD2
Reactivity: Human
WB, IF, IHC (p), EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-GAD65 Antibody
(hide)
Target
See all GAD65 (GAD2) Antibodies
GAD65 (GAD2)
(Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
Binding Specificity
All epitopes for GAD65 antibodies
AA 116-145, Middle Region
Reactivity
All reactivities for GAD65 antibodies
Human
Host
All hosts for GAD65 antibodies
Rabbit
Clonality
All clonalities for GAD65 antibodies
Polyclonal
Conjugate
All conjugates for GAD65 antibodies
This GAD65 antibody is un-conjugated
Application
All applications for GAD65 antibodies
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes Human GAD2 / GAD65 (Center).
Purification
Protein A column, followed by peptide affinity purification
Immunogen
KLH conjugated synthetic peptide between 116-145 amino acids from the Central region of Human GAD2 / GAD65 Genename: GAD2
Isotype
Ig Fraction
Top Product
Discover our top product GAD2 Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for GAD65
(hide)
Target
GAD65 (GAD2)
(Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
Alternative Name
GAD2 / GAD65 (GAD2 Products )
Synonyms
GAD65 antibody, gad65 antibody, F12P19.12 antibody, F12P19_12 antibody, GLUTAMATE DECARBOXYLASE 2 antibody, glutamate decarboxylase 2 antibody, zgc:112198 antibody, 6330404F12Rik antibody, GAD(65) antibody, Gad-2 antibody, glutamate decarboxylase 2 antibody, glutamate decarboxylase 1 antibody, glutamic acid decarboxylase 2 antibody, GAD2 antibody, PTRG_06148 antibody, LOC9324534 antibody, Gad2 antibody, GAD1 antibody, gad2 antibody
Background
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.Synonyms: 65 kDa glutamic acid decarboxylase, GAD-2, GAD-65, Glutamate decarboxylase 2, Glutamate decarboxylase 65 kDa isoform
Molecular Weight
65411 Da
Gene ID
2572
NCBI Accession
NP_000809
Recently viewed
(hide)