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MCM6 antibody (N-Term)
MCM6
Reactivity: Human
WB, IHC (p), EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MCM6 Antibody
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Target
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MCM6
(Minichromosome Maintenance Complex Component 6 (MCM6))
Binding Specificity
All epitopes for MCM6 antibodies
AA 79-109, N-Term
Reactivity
All reactivities for MCM6 antibodies
Human
Host
All hosts for MCM6 antibodies
Rabbit
Clonality
All clonalities for MCM6 antibodies
Polyclonal
Conjugate
All conjugates for MCM6 antibodies
This MCM6 antibody is un-conjugated
Application
All applications for MCM6 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody recognizes Human MCM6 (N-term). Other species not tested.
Purification
Protein A column, followed by peptide affinity purification
Immunogen
KLH conjugated synthetic peptide between 79-109 amino acids from the N-terminal region of human MCM6
Isotype
Ig Fraction
Top Product
Discover our top product MCM6 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for MCM6
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Target
MCM6
(Minichromosome Maintenance Complex Component 6 (MCM6))
Alternative Name
MCM6 (MCM6 Products )
Synonyms
CG4039 antibody, DmMCM6 antibody, DmeMCM6 antibody, Dmel\\CG4039 antibody, MCM6 antibody, McM6 antibody, fs(1)K1214 antibody, mcm6 antibody, MCG40308 antibody, Mis5 antibody, P105MCM antibody, Mcmd6 antibody, mis5 antibody, mmcm6 antibody, ASP-l1 antibody, D1Wsu22e antibody, Minichromosome maintenance 6 antibody, DNA replication licensing factor MCM6 antibody, minichromosome maintenance complex component 6 antibody, minichromosome maintenance complex component 6 L homeolog antibody, DNA replication licensing factor mcm-6 antibody, Mcm6 antibody, TP02_0113 antibody, PVX_114735 antibody, CMU_027970 antibody, MCM6 antibody, mcm6.L antibody, mcm-6 antibody
Background
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.Synonyms: DNA replication licensing factor MCM6, Mis5, P105MCM, minichromosome maintenance complex component 6
Molecular Weight
92889 Da
Gene ID
4175
NCBI Accession
NP_005906
Pathways
DNA Damage Repair , Mitotic G1-G1/S Phases , DNA Replication , Synthesis of DNA
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