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FOXO4 antibody (Forkhead Box O4)

Details for Product anti-FOXO4 Antibody No. ABIN965517, Supplier: Log in to see
Antigen
  • afx
  • AFX
  • AFX1
  • Afxh
  • FOXO4
  • foxo4
  • MLLT7
  • Mllt7
  • RGD1561201
Alternatives
anti-Human FOXO4 antibody for Western Blotting
Reactivity
Human, Mouse (Murine), Rat (Rattus)
245
143
101
7
5
2
1
1
1
1
1
Host
Rabbit
222
16
8
Clonality
Polyclonal
Conjugate
This FOXO4 antibody is un-conjugated
6
6
6
6
3
3
3
3
3
3
3
3
3
3
3
1
Application
Western Blotting (WB)
182
94
78
36
33
32
21
8
5
Supplier
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human AFX around the phosphorylation site of serine 197.
Specificity AFX (Ab-197) antibody detects endogenous levels of total AFX protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name AFX (FOXO4 Antibody Abstract)
Pathways Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes WB: 1:500~1:1000.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Moody, Scott, Amirghahari, Nathan, Young, Dawson, Sixbey: "Modulation of the cell growth regulator mTOR by Epstein-Barr virus-encoded LMP2A." in: Journal of virology, Vol. 79, Issue 9, pp. 5499-506, 2005 (PubMed).

Brugarolas, Lei, Hurley, Manning, Reiling, Hafen, Witters, Ellisen, Kaelin: "Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex." in: Genes & development, Vol. 18, Issue 23, pp. 2893-904, 2004 (PubMed).

Kumar, Pandey, Sabatini, Kumar, Majumder, Bharti, Carmichael, Kufe, Kharbanda: "Functional interaction between RAFT1/FRAP/mTOR and protein kinase cdelta in the regulation of cap-dependent initiation of translation." in: The EMBO journal, Vol. 19, Issue 5, pp. 1087-97, 2000 (PubMed).

Gingras, Kennedy, OLeary, Sonenberg, Hay: "4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway." in: Genes & development, Vol. 12, Issue 4, pp. 502-13, 1998 (PubMed).

Background publications Burnett, Barrow, Cohen, Snyder, Sabatini: "RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 4, pp. 1432-7, 1998 (PubMed).