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FOXO4 Products

(Forkhead Box O4 (FOXO4))
This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010].

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Featured FOXO4 Categories

FOXO4 Antibodies

High quality antibodies with extensive validation data.

FOXO4 ELISA Kits

Reliable ELISA kits for a wide range of species.

FOXO4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FOXO4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, ICC, IF, IHC, WB
Validations
  • (14)
Cat. No. ABIN6256565
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, ICC, IF, IHC, WB
Validations
  • (11)
Cat. No. ABIN6255069
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, ICC, IF, IHC, WB
Validations
  • (3)
Cat. No. ABIN6259818
Quantity 100 μL
Datasheet Datasheet

Recommended FOXO4 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380585
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380746
Quantity 2 x 96 tests
Datasheet Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380482
Quantity 2 x 96 tests
Datasheet Datasheet

Recommended FOXO4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3092649
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3137543
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN2721373
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our FOXO4 products

Pierce, Podlutskaya, Halloran, Hussong, Lin, Burbank, Hart, Galvan: "Over-expression of heat shock factor 1 phenocopies the effect of chronic inhibition of TOR by rapamycin and is sufficient to ameliorate Alzheimer's-like deficits in mice modeling the disease." in: Journal of neurochemistry, Vol. 124, Issue 6, pp. 880-93, (2013) (PubMed).

Zhan, Wang, Li, Xu, Sun, Xu: "Activation of Akt/FoxO signaling pathway contributes to induction of neuroprotection against transient global cerebral ischemia by hypoxic pre-conditioning in adult rats." in: Journal of neurochemistry, Vol. 114, Issue 3, pp. 897-908, (2010) (PubMed).

Paik, Kollipara, Chu, Ji, Xiao, Ding, Miao, Tothova, Horner, Carrasco, Jiang, Gilliland, Chin, Wong, Castrillon, DePinho: "FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis." in: Cell, Vol. 128, Issue 2, pp. 309-23, (2007) (PubMed).

Di, Hao, Gao, Wang, Wang, Qiu, Wen, Zhou, Wu, Lu, Liao, Mei, Zheng, Che: "Monoclonal antibody-based antigen capture enzyme-linked immunosorbent assay reveals high sensitivity of the nucleocapsid protein in acute-phase sera of severe acute respiratory syndrome patients." in: Clinical and diagnostic laboratory immunology, Vol. 12, Issue 1, pp. 135-40, (2005) (PubMed).

Moody, Scott, Amirghahari, Nathan, Young, Dawson, Sixbey: "Modulation of the cell growth regulator mTOR by Epstein-Barr virus-encoded LMP2A." in: Journal of virology, Vol. 79, Issue 9, pp. 5499-506, (2005) (PubMed).

Di Maira, Salvi, Arrigoni, Marin, Sarno, Brustolon, Pinna, Ruzzene: "Protein kinase CK2 phosphorylates and upregulates Akt/PKB." in: Cell death and differentiation, Vol. 12, Issue 6, pp. 668-77, (2005) (PubMed).

Brugarolas, Lei, Hurley, Manning, Reiling, Hafen, Witters, Ellisen, Kaelin: "Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex." in: Genes & development, Vol. 18, Issue 23, pp. 2893-904, (2004) (PubMed).

Essers, Weijzen, de Vries-Smits, Saarloos, de Ruiter, Bos, Burgering: "FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK." in: The EMBO journal, Vol. 23, Issue 24, pp. 4802-12, (2004) (PubMed).

Crossley: "Neutrophil activation by fMLP regulates FOXO (forkhead) transcription factors by multiple pathways, one of which includes the binding of FOXO to the survival factor Mcl-1." in: Journal of leukocyte biology, Vol. 74, Issue 4, pp. 583-92, (2003) (PubMed).

Tang, Lasky: "The forkhead transcription factor FOXO4 induces the down-regulation of hypoxia-inducible factor 1 alpha by a von Hippel-Lindau protein-independent mechanism." in: The Journal of biological chemistry, Vol. 278, Issue 32, pp. 30125-35, (2003) (PubMed).

Synonyms and alternative names related to FOXO4

forkhead box O4 (FOXO4), forkhead box O4 L homeolog (foxo4.L), forkhead box O4 (Foxo4), AFX, afx, AFX1, Afxh, FOXO4, foxo4, MLLT7, Mllt7, RGD1561201

Protein level used designations for FOXO4

  • similar to Putative fork head domain transcription factor AFX1 (Forkhead box protein O4)
  • forkhead box O4
  • forkhead box protein O4-like
  • fork head domain transcription factor AFX1
  • forkhead box protein O4
  • myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 7
  • forkhead protein
  • myeloid/lymphoid or mixed lineage-leukemia translocation to 7 homolog
  • forkhead box O1A
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