anti-Estrogen Receptor alpha antibody (Estrogen Receptor 1)

Details for Product anti-ESR1 Antibody No. ABIN966105, Supplier: Login to see New
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Antigen
Synonyms
ACTGP1, ACT1GP1, HY-psi-gamma-AC6, ER[b]2, ER[b]a, zfER[b]2, zfER-beta2, XER, era, esr, esra, nr3a1, ERbeta, xesr-1, ERalpha, xlERalpha1, xlERalpha2, LOC398733, LOC398734, 2610524P08Rik, 9130407C09Rik ... show more
ACTGP1, ACT1GP1, HY-psi-gamma-AC6, ER[b]2, ER[b]a, zfER[b]2, zfER-beta2, XER, era, esr, esra, nr3a1, ERbeta, xesr-1, ERalpha, xlERalpha1, xlERalpha2, LOC398733, LOC398734, 2610524P08Rik, 9130407C09Rik, AU019798, Era, M-ERA, MERA-S, MERA-W, ERA, ERAL1A, H-ERA, HERA-A, HERA-B, er, esr1, ER, ESR, ESRA, ESTRR, NR3A1, ER-alpha, Esr, RNESTROR, ERALPHA, ER[a], eralpha, zfER[a], ESR1, AA420328, AU041214, ERa, Estr, Estra, Nr3a1 show less
Alternatives
Reactivity
Human
(880), (312), (175), (28), (15), (10), (9), (7), (6), (4), (3), (2), (2), (1), (1)
Host
Rabbit
(688), (234), (10), (3), (3)
Clonality
Polyclonal
Conjugate
This Estrogen Receptor alpha antibody is un-conjugated
(35), (31), (28), (14), (14), (14), (10), (8), (8), (8), (8), (8), (8), (8), (8)
Application
Immunohistochemistry (IHC)
(679), (300), (294), (196), (132), (92), (85), (41), (35), (18), (10), (9), (8), (8), (4), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Quantity 100 μg
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human Estrogen Receptor- around the phosphorylation site of serine167 (L-A-SP-T-N).
Specificity Estrogen Receptor- (Ab-167) antibody detects endogenous levels of total Estrogen Receptor- protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name Estrogen Receptor-alpha (ESR1 Antibody Abstract)
Pathways Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Shah, Rowan: "The Src kinase pathway promotes tamoxifen agonist action in Ishikawa endometrial cells through phosphorylation-dependent stabilization of estrogen receptor (alpha) promoter interaction and elevated steroid receptor coactivator 1 activity." in: Molecular endocrinology (Baltimore, Md.), Vol. 19, Issue 3, pp. 732-48, 2005 (PubMed).

Campbell, Bhat-Nakshatri, Patel et al.: "Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance." in: The Journal of biological chemistry, Vol. 276, Issue 13, pp. 9817-24, 2001 (PubMed).

Catalog No. ABIN966105
$398.75
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