Met Proto-Oncogene (Hepatocyte Growth Factor Receptor) (MET) antibody

Antigen: Met Proto-Oncogene (Hepatocyte Growth Factor Receptor) (MET)

Synonyms: SF, HGFB, HPTA, F-TCF, DFNB39, NK1, NK2, HGF/SF, SF/HGF, C230052L06Rik, HGF, CACNA2D1, MET

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse (Murine), Rat (Rattus)

Conjugate: Un-conjugated

Application: Immunohistochemistry (IHC)

Catalog no.: ABIN966572

Additional Information

Alternative name: Met

Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human Met around the phosphorylation site of tyrosine 1349 (E-H-YP-V-H).

Specificity: Met (Ab-1349) antibody detects endogenous levels of total Met protein.

Application Details

Application Notes: WB: 1:500~1:1000.

Concentration: 100ug/100ul.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Preservative: 0.02% Sodium Azide

Storage: Store at -20°C/1 year.

Restrictions: For Research Use only

Publications

Product: Ponzetto, Bardelli, Maina et al.: "A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor." in: Molecular and cellular biology, Vol. 13, Issue 8, pp. 4600-8, 1993 (PubMed).

Plopper, McNamee, Dike et al.: "Convergence of integrin and growth factor receptor signaling pathways within the focal adhesion complex." in: Molecular biology of the cell, Vol. 6, Issue 10, pp. 1349-65, 1996 (PubMed).

Fan, Ma, Gao et al.: "The multisubstrate adapter Gab1 regulates hepatocyte growth factor (scatter factor)-c-Met signaling for cell survival and DNA repair." in: Molecular and cellular biology, Vol. 21, Issue 15, pp. 4968-84, 2001 (PubMed).

Jackson, Galinha, Pereira et al.: "Rapid deposition of extensin during the elicitation of grapevine callus cultures is specifically catalyzed by a 40-kilodalton peroxidase." in: Plant physiology, Vol. 127, Issue 3, pp. 1065-76, 2001 (PubMed).

Schiering, Knapp, Marconi et al.: "Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 22, pp. 12654-9, 2003 (PubMed).