AGT antibody
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- Target See all AGT Antibodies
- AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This AGT antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human AGT expressed in E. coli.
- Clone
- 1B1
- Isotype
- IgG2b
- Top Product
- Discover our top product AGT Primary Antibody
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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Role of cardiac overexpression of ANG II in the regulation of cardiac function and remodeling postmyocardial infarction." in: American journal of physiology. Heart and circulatory physiology, Vol. 293, Issue 3, pp. H1900-7, (2007) (PubMed).
: "Adrenomedullin inhibits angiotensin II-induced contraction in human aortic smooth muscle cells." in: Regulatory peptides, Vol. 133, Issue 1-3, pp. 155-9, (2005) (PubMed).
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Role of cardiac overexpression of ANG II in the regulation of cardiac function and remodeling postmyocardial infarction." in: American journal of physiology. Heart and circulatory physiology, Vol. 293, Issue 3, pp. H1900-7, (2007) (PubMed).
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- Target
- AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))
- Alternative Name
- AGT (AGT Products)
- Synonyms
- ANHU antibody, SERPINA8 antibody, AI265500 antibody, AngI antibody, AngII antibody, Aogen antibody, Serpina8 antibody, ANRT antibody, Ang antibody, PAT antibody, wu:fb62f06 antibody, wu:fj87b02 antibody, zgc:111892 antibody, AGT antibody, angt antibody, ANGT antibody, angiotensinogen antibody, angiotensinogen (serpin peptidase inhibitor, clade A, member 8) antibody, AGT antibody, Agt antibody, agt antibody
- Background
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Description: AGT, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
Aliases: ANHU
- Molecular Weight
- 53 kDa
- Gene ID
- 183
- HGNC
- 183
- Pathways
- JAK-STAT Signaling, ACE Inhibitor Pathway, EGFR Signaling Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Feeding Behaviour, Monocarboxylic Acid Catabolic Process, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Regulation of long-term Neuronal Synaptic Plasticity
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