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Browse our anti-Caspase 1, Apoptosis-Related Cysteine Peptidase (Interleukin 1, Beta, Convertase) (CASP1) Antibodies

Full name:
anti-Caspase 1, Apoptosis-Related Cysteine Peptidase (Interleukin 1, Beta, Convertase) Antibodies (CASP1)
On www.antibodies-online.com are 0 Caspase 1, Apoptosis-Related Cysteine Peptidase (Interleukin 1, Beta, Convertase) (CASP1) Antibodies from different suppliers available. A total of 0 Caspase 1, Apoptosis-Related Cysteine Peptidase (Interleukin 1, Beta, Convertase) products are currently listed.
Synonyms:
CASP1, ccp1, CG5370, dcp-1, dcp1, Dmel\\CG5370, ICE, IL1BC, l(2)01862, l(2)02132, P45
list all antibodies Gene Name GeneID UniProt
Anti-Rat CASP1 CASP1 25166  
Anti-Human CASP1 CASP1 834 P29466
Anti-Mouse CASP1 CASP1 12362 P29452

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More Antibodies against Caspase 1, Apoptosis-Related Cysteine Peptidase (Interleukin 1, Beta, Convertase) Interaction Partners

Human Caspase 1, Apoptosis-Related Cysteine Peptidase (Interleukin 1, Beta, Convertase) (CASP1) interaction partners

  1. These results suggest that released caspase-1 exists in a unique complex that is functionally stable and protected from immunodepletion whereas cell-extract generated active caspase-1 is rapidly inhibited in the cytosolic milieu.

  2. Genetic polymorphisms in Nalp3 (show NLRP3 Antibodies) and caspase-1 may be associated with individual susceptibility to silicosis, especially when the polymorphisms interact with age, cumulative dust exposure, or smoking status.

  3. In contrast, inhibition of the protease activity of Kgp, RgpA or RgpB increased the human caspase-1-activating potential of wild-type Porphyromonas gingivalis, indicating an inhibitory effect of the collaborative action of gingipains.

  4. NLRP3 (show NLRP3 Antibodies) and caspase-1 are expressed in the odontoblast layers in normal human dental pulp tissue, whereas in inflamed pulp tissue, the odontoblast layers are disrupted and dental pulp cells are positive for NLRP3 (show NLRP3 Antibodies) and caspase-1.

  5. the rs713875 IBD risk polymorphism increases MTMR3 (show MTMR3 Antibodies) expression, which modulates pattern recognition receptor (PRR (show PVRL1 Antibodies))-induced outcomes, including increased induced caspase-1 activation

  6. specific caspase (show CASP3 Antibodies) cleavage sites in Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen function to blunt apoptosis as well as interfere with the caspase-1-mediated inflammasome

  7. three cofactor independent human monoclonal aPL (show FASL Antibodies) can induce transcription of NLRP3 (show NLRP3 Antibodies) and caspase-1 resulting in inflammasome activation specific for NLRP3 (show NLRP3 Antibodies), which depends fully on activation of endosomal NADPH-oxidase-2 (NOX2 (show CYBB Antibodies)) by aPL (show FASL Antibodies)

  8. Internalized Cryptococcus neoformans Activates the Canonical Caspase-1 and the Noncanonical Caspase-8 (show CASP8 Antibodies) Inflammasomes.

  9. In patients with HIV, serum CASP1 levels in a group with high CD4 (show CD4 Antibodies) cell counts increased rapidly then decreased within a short time during early HIV-1 infection. In contrast, CASP1 levels in the CD4Low group were increased after 1 year of HIV-1 infection.

  10. production of 20-kDa IL-1beta (show IL1B Antibodies) may act to limitIL-1beta signaling by reducing the pool of pro-IL-1beta (show IL1B Antibodies) availability for caspase-1 cleavage

Mouse (Murine) Caspase 1, Apoptosis-Related Cysteine Peptidase (Interleukin 1, Beta, Convertase) (CASP1) interaction partners

  1. study uncovered an important role for YopJ in inhibiting caspase-1 in activated macrophages and in promoting Yersinia virulence

  2. Caspase-1-activated IL-18 (show IL18 Antibodies) induces IFN-gamma (show IFNG Antibodies) to prime caspase-11 (show CASP4 Antibodies) and rapidly clear Burkholderia thailandensis infection.

  3. These results argue that caspase-1, -4 or -5 can be recruited to inflammasomes under specific circumstances, often leading to distinctly organized and localized complexes that may impact the functions of these proteases

  4. The resilience of casp1(-/-) mice to SIRS lethality is associated with a lower inflammatory response, loss of hippocampal gene coexpression patterns, and increased hippocampal Adamts1 (show ADAMTS1 Antibodies) gene expression.

  5. Internalized Cryptococcus neoformans Activates the Canonical Caspase-1 and the Noncanonical Caspase-8 (show CASP8 Antibodies) Inflammasomes.

  6. This study highlights a critical role of caspase-1 activation and NLPR3/ASC (show STS Antibodies) inflammasome complex in the down-modulation of IL-33 (show IL33 Antibodies) in vivo and in vitro.

  7. Data show that caspase-1 but not caspase-11 (show CASP4 Antibodies) was essential for the functional activities of the NLRC4 (show NLRC4 Antibodies) inflammasome.

  8. Data indicate that genetic ablation of caspase-1 and -11 from cpdm (show SHARPIN Antibodies) mice significantly reduced skin inflammation in sharpin (show SHARPIN Antibodies)-deficient mice.

  9. In an inflammatory microenvironment, caspase-1 is regulated by NF-kappaB (show NFKB1 Antibodies).

  10. ASC (show STS Antibodies)-driven caspase-1 autoprocessing and speck formation are dispensable for the activation of caspase-1 and the NLRP1b inflammasome.

Pig (Porcine) Caspase 1, Apoptosis-Related Cysteine Peptidase (Interleukin 1, Beta, Convertase) (CASP1) interaction partners

  1. Src kinase (show CSK Antibodies) mediates hypoxia-induced caspase-1 activation in the cerebral cortex of newborn piglets

  2. endometrial expression of CASP1 and IL18 (show IL18 Antibodies) associated with pregnancy establishment; alteration of CASP1 and IL18 (show IL18 Antibodies) following premature exposure of uterus to estrogen during early pregnancy may contribute to conceptus loss between Days 15 to 18 of pregnancy

Fruit Fly (Drosophila melanogaster) Caspase 1, Apoptosis-Related Cysteine Peptidase (Interleukin 1, Beta, Convertase) (CASP1) interaction partners

  1. drICE (show CASP3 Antibodies) and dcp-1 (show ACE Antibodies) function in cell death redundantly. However, dying neurons in a few clusters strictly required drICE (show CASP3 Antibodies) but not dcp-1 (show ACE Antibodies), but required drICE (show CASP3 Antibodies) and dcp-1 (show ACE Antibodies) when drICE (show CASP3 Antibodies) activity was reduced via hypomorphic mutation.

  2. Drosophila corazonin-producing interneuron programmed cell death utilizes dronc, strica, dcp-1 (show ACE Antibodies), and ice

  3. Autophagy suppresses Dcp-1 (show ACE Antibodies)-mediated apoptotic cell death, whereas Dcp-1 (show ACE Antibodies) positively regulates autophagy, possibly through feedback regulation.

  4. novel characteristic morphological features of egg chambers lacking both dcp-1 (show ACE Antibodies) and pita functions in the germline cells; suggested an essential role of dcp-1 (show ACE Antibodies) and/or pita during mid-oogenesis

  5. A double-mutant analysis between drICE (show CASP3 Antibodies) and death caspase-1 (dcp-1), another effector caspase (show CASP3 Antibodies), reveals that some cells (type I) strictly require drICE (show CASP3 Antibodies) for apoptosis, whereas other cells (type II) require either drICE (show CASP3 Antibodies) or dcp-1 (show ACE Antibodies).

  6. Data show that the effector caspase Dcp-1 and the inhibitor of apoptosis protein (show BIRC2 Antibodies) Bruce (show BIRC6 Antibodies) function to regulate both autophagy and starvation-induced cell death in Drosophila.

  7. HeT-A mRNA is derepressed in mRNA degradation mutants dcp1 (show ACE Antibodies), indicating that the enzyme also aid in removing full-length transcripts and/or decay intermediates.

Silk Worm Caspase 1, Apoptosis-Related Cysteine Peptidase (Interleukin 1, Beta, Convertase) (CASP1) interaction partners

  1. Activation of Atg5 (show ATG5 Antibodies), AIF (show AIFM1 Antibodies) and caspase (show CASP3 Antibodies) genes in close association with different cell death events revealed the synchronized differential expression of apoptosis-associated genes in response to macroparasitism.

Caspase 1, Apoptosis-Related Cysteine Peptidase (Interleukin 1, Beta, Convertase) (CASP1) Antigen Profile

Antigen Summary

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.

Alternative names and synonyms associated with Caspase 1, Apoptosis-Related Cysteine Peptidase (Interleukin 1, Beta, Convertase) (CASP1)

  • caspase 1 (Casp1) antibody
  • caspase 1, apoptosis-related cysteine peptidase (CASP1) antibody
  • caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) (CASP1) antibody
  • caspase 4, apoptosis-related cysteine peptidase (CASP4) antibody
  • caspase-1-like (LOC100725217) antibody
  • caspase 1 (LOC100101588) antibody
  • Death caspase-1 (Dcp-1) antibody
  • caspase-1 (Ice) antibody
  • caspase-1 (AaeL_AAEL014348) antibody
  • CASP1 antibody
  • ccp1 antibody
  • CG5370 antibody
  • dcp-1 antibody
  • dcp1 antibody
  • Dmel\\CG5370 antibody
  • ICE antibody
  • IL1BC antibody
  • l(2)01862 antibody
  • l(2)02132 antibody
  • P45 antibody

Protein level used designations for CASP1

CASP-1 , IL-1 beta-converting enzyme , IL-1BC , Interleukin 1beta converting enzyme , caspase-1 , interleukin 1, beta, convertase , interleukin-1 beta convertase , interleukin-1 beta-converting enzyme , p45 , ICE , caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) , CASP1 nirs variant 1 , IL1B-convertase , interleukin 1-B converting enzyme , IL-1B converting enzyme , interleukin 1 beta-converting enzyme , caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase) , interleukin-1 beta converting enzyme , caspase-1/caspase-4 hybrid , CG5370-PA , Dcp-1-PA , caspase , caspase 1 , death caspase-1

GENE ID SPECIES
25166 Rattus norvegicus
100033888 Equus caballus
834 Homo sapiens
12362 Mus musculus
395764 Gallus gallus
397319 Sus scrofa
514214 Bos taurus
403724 Canis lupus familiaris
100725217 Cavia porcellus
100101588 Oryctolagus cuniculus
493961 Felis catus
37729 Drosophila melanogaster
451519 Pan troglodytes
692604 Bombyx mori
5564196 Aedes aegypti
100437679 Pongo abelii
100588974 Nomascus leucogenys
706568 Macaca mulatta
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