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anti-Human Caspase 1 antibody for Immunoprecipitation

Recommended Caspase 1 Antibody (supplied by: Log in to see )

Antigen
Caspase 1 (CASP1) Antibodies
  • CASP1
  • ccp1
  • CG5370
  • dcp-1
  • DCP-1
  • dcp1
  • DCP1
  • Dcp1
  • Dmel\\CG5370
  • ICE
  • Ice
  • Il1bc
  • IL1BC
  • l(2)01862
  • l(2)02132
  • P45
Reactivity
Human, Mouse (Murine), Rat (Rattus)
245
72
50
8
2
2
1
1
1
1
1
1
Host
Rabbit
231
36
10
2
Clonality
Polyclonal
Conjugate
This Caspase 1 antibody is un-conjugated
19
14
8
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
225
127
119
75
23
18
16
6
6
5
3
2
2
Supplier
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Catalog No. ABIN222877
$ 336.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008941957 ABIN126963 IF IP WB Rabbit Log in to see Polyclonal
0.0008941957 ABIN2704574 IP IHC WB Rabbit C-Term Log in to see Polyclonal
0.0008941957 ABIN615144 IHC (p) IP WB Rabbit Log in to see Polyclonal
0.0008941957 ABIN200369 ICC IP WB Rabbit AA 129-152 Log in to see Polyclonal
0.0008941957 ABIN241601 IP WB Rabbit Log in to see Polyclonal
0.0008941957 ABIN1732658 IHC (p) IP IHC WB Rabbit IgG Log in to see Polyclonal
0.0008941957 ABIN333789 IP IHC WB Rabbit N-Term Log in to see Polyclonal
0.0008941957 ABIN1585732 IP IHC ELISA WB Rabbit C-Term Log in to see Polyclonal
0.0008941957 ABIN1001991 IF IP WB Rabbit Log in to see Polyclonal
0.0008941957 ABIN184375 IHC (fro) IP WB Rabbit Log in to see Polyclonal
0.0008941957 ABIN2219321 IF IP WB Rabbit IgG Log in to see Polyclonal
0.0008941957 ABIN187803 IF IP WB Rabbit Log in to see Polyclonal
0.0008941957 ABIN2218936 IC IP IHC WB Rabbit IgG AA 224-242 Log in to see Polyclonal
0.0008941957 ABIN2467373 IP IHC WB Rabbit Log in to see Polyclonal
0.0008941957 ABIN2327673 IP ELISA WB Mouse IgG1 kappa Log in to see 3G225
0.0008941957 ABIN2327670 IP IHC ELISA WB Rabbit IgG Log in to see Polyclonal
0.0008941957 ABIN4288001 ICC IF IP WB Rabbit Log in to see Polyclonal
0.0008941957 ABIN4288002 ICC IF IP WB Rabbit Log in to see Polyclonal
0.0008941957 ABIN2135437 IF IP WB Rabbit IgG Log in to see Polyclonal
0.0008941957 ABIN2218725 IP IHC WB Rabbit Log in to see Polyclonal

Top referenced anti-Caspase 1 antibody for Immunoprecipitation

Similar anti-Caspase 1 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine) Human
ELISA 12 Antibodies 18 Antibodies 101 Antibodies
Immunocytochemistry (ICC) 3 Antibodies 4 Antibodies
Immunofluorescence (IF) 7 Antibodies 8 Antibodies
Immunohistochemistry (IHC) 32 Antibodies 39 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 25 Antibodies 29 Antibodies
Immunoprecipitation (IP) 9 Antibodies 11 Antibodies
Western Blotting (WB) 46 Antibodies 65 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 6 Antibodies

General

Antigen Caspase 1 (CASP1) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(245), (72), (50), (8), (2), (2), (1), (1), (1), (1), (1), (1)
Host Rabbit
(231), (36), (10), (2)
Clonality
Polyclonal
Conjugate This Caspase 1 antibody is un-conjugated
(19), (14), (8), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
(225), (127), (119), (75), (23), (18), (16), (6), (6), (5), (3), (2), (2)
Pubmed 5 references available
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Product Details anti-Caspase 1 Antibody

Target Details Caspase 1 Application Details Handling References for anti-Caspase 1 Antibody (ABIN222877) Images
Blocking Peptide Blocking peptide for this product available: ABIN412645
Specificity The immunoaffinity purified antibody recognizes 45 kDa procaspase-1 and the 20 kDa cleaved product.
Purification Affinity purified
Immunogen Synthetic peptide surrounding amino acid 132 of human caspase-1
Isotype IgG

Target Details Caspase 1

Product Details anti-Caspase 1 Antibody Application Details Handling References for anti-Caspase 1 Antibody (ABIN222877) Images back to top
Antigen
Alternative Name Caspase-1 (CASP1 Antibody Abstract)
Background Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-1 (ICE, interleukin-1β-converting enzyme) is the mammalian caspase responsible for the proteolytic conversion of the proforms of interleukin-1β and IL-18 into active cytokines. Like other caspases, Caspase-1 itself is synthesized as a pro-enzyme that is cleaved during activation into a large (20 kDa) and small (10 kDa) subunits. The cellular role of caspase-1 appears limited to cytokine activation as they do not have obvious roles in apoptosis.
Synonyms: CASP1, IL1BCE, P45, Interleukin-1 beta convertase, IL-1BC, IL1BC, p45, IL1B-convertase, CASP-1, ICE
Gene ID 834
NCBI Accession NP_150636
Research Area Apoptosis/Necrosis
Pathways Apoptosis

Application Details

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Handling References for anti-Caspase 1 Antibody (ABIN222877) Images back to top
Application Notes Western blot analysis (0.5-4 μg/mL), Immunoprecipitation (4-8 μg/mL) and Immunofluorescence (10-20 μg/mL).
Comment

Country of Animal Origin: China

Restrictions For Research Use only

Handling

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Application Details References for anti-Caspase 1 Antibody (ABIN222877) Images back to top
Format Liquid
Concentration 0.2 mg/mL
Buffer 100 μg (0.2 mg/mL) affinity purified rabbit anti-caspase-1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
Storage -20 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months

References for anti-Caspase 1 Antibody (ABIN222877)

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Application Details Handling Images back to top
Product cited in:

Martin, Shaw, Liu, Steiger, Harper: "MSU crystal-recruited non-inflammatory monocytes differentiate into M1-like pro-inflammatory macrophages in a peritoneal murine model of gout." in: Arthritis and rheumatism, 2011

Martin, Shaw, Liu, Steiger, Harper: "Monosodium urate monohydrate crystal-recruited noninflammatory monocytes differentiate into M1-like proinflammatory macrophages in a peritoneal murine model of gout." in: Arthritis and rheumatism, Vol. 63, Issue 5, pp. 1322-32, 2011

Shi, Wang, Li, Sahbaie, Kingery, Clark: "Neuropeptides contribute to peripheral nociceptive sensitization by regulating interleukin-1β production in keratinocytes." in: Anesthesia and analgesia, Vol. 113, Issue 1, pp. 175-83, 2011 (1:200).

Peluffo, Bussmann, Stouffer, Tesone: "Expression of caspase-2, -3, -8 and -9 proteins and enzyme activity in the corpus luteum of the rat at different stages during the natural estrous cycle." in: Reproduction (Cambridge, England), Vol. 132, Issue 3, pp. 465-75, 2006

Sasaki, Ikeda, Sato, Nakanuma: "Decreased expression of Bmi1 is closely associated with cellular senescence in small bile ducts in primary biliary cirrhosis." in: The American journal of pathology, Vol. 169, Issue 3, pp. 831-45, 2006

Images

Product Details anti-Caspase 1 Antibody Target Details Caspase 1 Application Details Handling References for anti-Caspase 1 Antibody (ABIN222877) back to top
Supplier Images
Western Blotting (WB) image for anti-Caspase 1 antibody (CASP1) (ABIN222877) Western blot analysis of Caspase-1 expression in Rat liver tissue lysate.