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anti-Human CD11b antibody for Multiplex Assay

Recommended CD11b Antibody (supplied by: Log in to see )

Antigen
Integrin alpha M (ITGAM) Antibodies
  • CD11b/CD18
  • CR3
  • CR3A
  • Cd11b
  • F730045J24Rik
  • Ly-40
  • MAC1
  • Mac-1
  • Mac-1a
  • CD11B
  • MAC-1
  • MAC1A
  • MO1A
  • SLEB6
  • C3bi
  • integrin, alpha M (complement component 3 receptor 3 subunit)
  • integrin alpha M
  • integrin, alpha M
  • ITGAM
  • Itgam
Reactivity
Human
684
472
194
78
31
19
17
15
13
11
9
9
8
7
5
4
4
4
2
2
Host
Mouse
488
369
160
17
5
2
Clonality
Monoclonal
Conjugate
This CD11b antibody is un-conjugated
148
119
88
48
19
19
15
14
14
14
13
11
10
9
9
9
8
8
7
7
6
6
6
6
5
4
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
1
Application
Multiplex Assay (MA)
835
234
228
172
163
139
96
94
94
67
26
21
21
13
8
6
5
5
4
3
3
2
1
1
1
1
1
1
1
1
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Catalog No. ABIN2664159
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Top referenced anti-CD11b antibody for Multiplex Assay

Similar anti-CD11b Antibodies

Application / Reactivity Human
Biochemical Assay (BCA) 3 Antibodies
Blocking Antibody (Inhibition) 1 Antibodies
Blocking Reagent (BR) 17 Antibodies
Cytometry by Time of Flight (CyTOF) 6 Antibodies
ELISA 77 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Flow Cytometry (FACS) 535 Antibodies
Functional Studies (Func) 61 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 84 Antibodies
Immunofluorescence (IF) 122 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 10 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 26 Antibodies
Immunohistochemistry (IHC) 123 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 11 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 118 Antibodies

General

Antigen Integrin alpha M (ITGAM) Antibodies
Reactivity Human
(684), (472), (194), (78), (31), (19), (17), (15), (13), (11), (9), (9), (8), (7), (5), (4), (4), (4), (2), (2)
Host Mouse
(488), (369), (160), (17), (5), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD11b antibody is un-conjugated
(148), (119), (88), (48), (19), (19), (15), (14), (14), (14), (13), (11), (10), (9), (9), (9), (8), (8), (7), (7), (6), (6), (6), (6), (5), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Multiplex Assay (MA)
(835), (234), (228), (172), (163), (139), (96), (94), (94), (67), (26), (21), (21), (13), (8), (6), (5), (5), (4), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 7 references available
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Product Details anti-CD11b Antibody

Target Details CD11b Application Details Handling References for anti-CD11b Antibody (ABIN2664159) Images
Cross-Reactivity Chimpanzee, Baboon, Cynomolgus, Rhesus Monkey, Marmoset, Pig (Porcine)
Purification The antibody was purified by affinity chromatography.
Clone ICRF44
Isotype IgG1 kappa

Target Details CD11b

Product Details anti-CD11b Antibody Application Details Handling References for anti-CD11b Antibody (ABIN2664159) Images back to top
Antigen
Alternative Name CD11b (ITGAM Antibody Abstract)
Background CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αM integrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2 (CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.
Research Area Stem Cells, Hematopoietic Progenitors, Hematopoietic Stem Cells, Glia marker, CD Antigens, Surface Receptors of Immune Cells
Pathways Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades

Application Details

Product Details anti-CD11b Antibody Target Details CD11b Handling References for anti-CD11b Antibody (ABIN2664159) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD11b Antibody Target Details CD11b Application Details References for anti-CD11b Antibody (ABIN2664159) Images back to top
Concentration 1.0 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and EDTA.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-CD11b Antibody (ABIN2664159)

Product Details anti-CD11b Antibody Target Details CD11b Application Details Handling Images back to top
Background publications

Charles, Hardwick, Daugas, Illei, Rivera: "Basophils and the T helper 2 environment can promote the development of lupus nephritis." in: Nature medicine, Vol. 16, Issue 6, pp. 701-7, 2010

David, Kacher, Specks, Aviram: "Interaction of proteinase 3 with CD11b/CD18 (beta2 integrin) on the cell membrane of human neutrophils." in: Journal of leukocyte biology, Vol. 74, Issue 4, pp. 551-7, 2003

Marsik, Halama, Cardona, Wlassits, Mayr, Pleiner, Jilma: "Regulation of Fas (APO-1, CD95) and Fas ligand expression in leukocytes during systemic inflammation in humans." in: Shock (Augusta, Ga.), Vol. 20, Issue 6, pp. 493-6, 2003

Jadhav, Bochner, Konstantopoulos: "Hydrodynamic shear regulates the kinetics and receptor specificity of polymorphonuclear leukocyte-colon carcinoma cell adhesive interactions." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 10, pp. 5986-93, 2001

Rezzonico, Imbert, Chicheportiche, Dayer et al.: "Ligation of CD11b and CD11c beta(2) integrins by antibodies or soluble CD23 induces macrophage inflammatory protein 1alpha (MIP-1alpha) and MIP-1beta production in primary human monocytes through a ..." in: Blood, Vol. 97, Issue 10, pp. 2932-40, 2001

Yoshino, Ami, Terao, Tashiro, Honda: "Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies." in: Experimental animals / Japanese Association for Laboratory Animal Science, Vol. 49, Issue 2, pp. 97-110, 2000

Stewart, Thiel, Hogg: "Leukocyte integrins." in: Current opinion in cell biology, Vol. 7, Issue 5, pp. 690-6, 1996

Images

Product Details anti-CD11b Antibody Target Details CD11b Application Details Handling References for anti-CD11b Antibody (ABIN2664159) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-CD11b antibody (Integrin alpha M) (ABIN2664159) anti-Integrin alpha M (ITGAM) antibody