anti-Rat (Rattus) CD11b antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended CD11b Antibody (supplied by: Log in to see )

Antigen
Integrin alpha M (ITGAM) Antibodies
  • CD11b/CD18
  • CR3
  • CR3A
  • Cd11b
  • F730045J24Rik
  • Ly-40
  • MAC1
  • Mac-1
  • Mac-1a
  • CD11B
  • MAC-1
  • MAC1A
  • MO1A
  • SLEB6
  • C3bi
  • integrin, alpha M (complement component 3 receptor 3 subunit)
  • integrin alpha M
  • integrin, alpha M
  • ITGAM
  • Itgam
Epitope
AA 50-100
48
39
24
19
15
15
15
13
8
6
6
5
5
5
5
4
4
4
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
732
514
191
79
31
19
17
15
13
11
10
9
8
7
5
4
4
4
4
2
Host
Rabbit
533
410
167
17
6
2
Clonality
Polyclonal
Conjugate
This CD11b antibody is un-conjugated
150
128
94
56
24
24
20
17
15
14
14
13
13
13
11
11
11
10
9
7
7
6
6
6
6
6
4
4
4
4
4
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
930
238
235
173
171
138
100
97
97
68
24
21
21
18
14
8
5
5
4
3
3
1
1
1
1
1
1
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN730918
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN258322 ICC FACS IF IHC (p) IHC WB Rabbit Internal Region, AA 500-600 Log in to see Polyclonal 16
1 ABIN120414 Func FACS IHC (fro) IHC (p) IP Mouse IgG2a Log in to see OX-42 4
1 ABIN3043258 IHC (p) WB Rabbit IgG AA 17-382 Log in to see Polyclonal 3
1 ABIN409930 FACS ICC IF IHC IHC (fro) IHC (p) SimWes WB Rabbit Internal Region, AA 250-350 Log in to see Polyclonal 24
1 ABIN120412 Func FACS IHC (fro) IF IHC (p) IP Mouse IgG2a Log in to see OX-42 4
1 ABIN120413 Func FACS IHC (fro) IHC (p) IP Mouse IgG2a Log in to see OX-42 4
1 ABIN4289448 FACS ICC IF IHC (fro) IHC (p) WB Alexa Fluor 488 Rabbit AA 250-350, Internal Region Log in to see Polyclonal 1
1 ABIN730927 IHC (p) WB HRP Rabbit IgG AA 50-100 Log in to see Polyclonal
1 ABIN1732800 FACS ICC IF IHC (p) WB Rabbit Internal Region, AA 250-350 Log in to see Polyclonal
1 ABIN741294 IHC (p) WB HRP Rabbit IgG AA 520-570 Log in to see Polyclonal
1 ABIN730920 IHC (p) WB Biotin Rabbit IgG AA 50-100 Log in to see Polyclonal
1 ABIN4289484 FACS ICC IF IHC IHC (p) WB Alexa Fluor 700 Rabbit AA 500-600, Internal Region Log in to see Polyclonal
1 ABIN4289482 FACS ICC IF IHC IHC (p) WB Alexa Fluor 488 Rabbit AA 500-600, Internal Region Log in to see Polyclonal
1 ABIN4289476 FACS ICC IF IHC IHC (p) WB DyLight 650 Rabbit AA 500-600, Internal Region Log in to see Polyclonal
1 ABIN4289477 FACS ICC IF IHC IHC (p) WB DyLight 550 Rabbit AA 500-600, Internal Region Log in to see Polyclonal
1 ABIN4289480 FACS ICC IF IHC IHC (p) WB DyLight 405 Rabbit AA 500-600, Internal Region Log in to see Polyclonal
1 ABIN4289478 FACS ICC IF IHC IHC (p) FITC Rabbit AA 500-600, Internal Region Log in to see Polyclonal
1 ABIN4289481 FACS ICC IF IHC IHC (p) WB Alexa Fluor 405 Rabbit AA 500-600, Internal Region Log in to see Polyclonal
1 ABIN4289483 FACS ICC IF IHC IHC (p) WB Alexa Fluor 647 Rabbit AA 500-600, Internal Region Log in to see Polyclonal
1 ABIN314167 ICC IF IHC IHC (p) WB Biotin Rabbit Internal Region, AA 500-600 Log in to see Polyclonal

General

Antigen Integrin alpha M (ITGAM) Antibodies
Epitope AA 50-100
(48), (39), (24), (19), (15), (15), (15), (13), (8), (6), (6), (5), (5), (5), (5), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(732), (514), (191), (79), (31), (19), (17), (15), (13), (11), (10), (9), (8), (7), (5), (4), (4), (4), (4), (2)
Host Rabbit
(533), (410), (167), (17), (6), (2)
Clonality
Polyclonal
Conjugate This CD11b antibody is un-conjugated
(150), (128), (94), (56), (24), (24), (20), (17), (15), (14), (14), (13), (13), (13), (11), (11), (11), (10), (9), (7), (7), (6), (6), (6), (6), (6), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(930), (238), (235), (173), (171), (138), (100), (97), (97), (68), (24), (21), (21), (18), (14), (8), (5), (5), (4), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 8 references available
Supplier Log in to see

Product Details anti-CD11b Antibody

Target Details CD11b Application Details Handling References for anti-CD11b antibody (ABIN730918) Images
Specificity The immunogen of this product has partial sequence similarity to CD11d and may cross react.
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human CD11b
Isotype IgG

Target Details CD11b

Product Details anti-CD11b Antibody Application Details Handling References for anti-CD11b antibody (ABIN730918) Images back to top
Antigen
Alternative Name CD11b/c (ITGAM Antibody Abstract)
Background

Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

Subcellular location: Extracellular

Synonyms: CR3A, MO1A, CD11B, MAC-1, MAC1A, SLEB6, Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, ITGAM, Integrin alpha-X, ITGAX, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150,95, CD11c

Gene ID 3684
UniProt P11215
Pathways Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation

Application Details

Product Details anti-CD11b Antibody Target Details CD11b Handling References for anti-CD11b antibody (ABIN730918) Images back to top
Application Notes WB 1:100-1000
FCM 1:20-100
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-CD11b Antibody Target Details CD11b Application Details References for anti-CD11b antibody (ABIN730918) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-CD11b antibody (ABIN730918)

Product Details anti-CD11b Antibody Target Details CD11b Application Details Handling Images back to top
Product cited in:

Yamaguchi, Sato, Kato-Itoh, Goto, Hara, Sanbo, Mizuno, Kobayashi, Yanagida, Umino, Ota, Hamanaka, Masaki, Rashid, Hirabayashi, Nakauchi: "Interspecies organogenesis generates autologous functional islets." in: Nature, Vol. 542, Issue 7640, pp. 191-196, 2017 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Mouse (Murine)).

Velázquez, Enos, McClellan, Cranford, Chatzistamou, Singh, Nagarkatti, Nagarkatti, Fan, Murphy: "MicroRNA-155 deletion promotes tumorigenesis in the azoxymethane-dextran sulfate sodium model of colon cancer." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 310, Issue 6, pp. G347-58, 2016

Kobayashi, Tanizaki, Kimura, Ishida, Nosaka, Toujima, Kuninaka, Minami, Ino, Kondo: "AG490, a Jak2 inhibitor, suppressed the progression of murine ovarian cancer." in: European journal of pharmacology, Vol. 766, pp. 63-75, 2015

Zhang, Hu, Liu, Ye, Gui, Zhou, Qi, He, Wang, Wang: "CD11b deficiency suppresses intestinal tumor growth by reducing myeloid cell recruitment." in: Scientific reports, Vol. 5, pp. 15948, 2015

Liu, Xie, Ma, Zhang, Liang, Shi, Yu, Feng, Zhang, Wu: "Gr-1+CD11b+ cells facilitate Lewis lung cancer recurrence by enhancing neovasculature after local irradiation." in: Scientific reports, Vol. 4, pp. 4833, 2014

Yu, Yang, Wang, Chen, Lu, Luo, Wang: "Ethanol supports macrophage recruitment and reinforces invasion and migration of lewis lung carcinoma." in: Alcoholism, clinical and experimental research, Vol. 38, Issue 10, pp. 2597-606, 2014

Long, Qiu, Wang, Yang, Jia, Xin, Wang, Han, Fei, Liu: "Genetically engineered bone marrow mesenchymal stem cells improve functional outcome in a rat model of epilepsy." in: Brain research, Vol. 1532, pp. 1-13, 2013

Long, Qiu, Liu, Fei, Feng, Wang, Zhong, Yi, Liu, Zhang, Han: "Functional recovery and neuronal regeneration of a rat model of epilepsy by transplantation of Hes1-down regulated bone marrow stromal cells." in: Neuroscience, Vol. 212, pp. 214-24, 2012

Images

Product Details anti-CD11b Antibody Target Details CD11b Application Details Handling References for anti-CD11b antibody (ABIN730918) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Integrin alpha M (ITGAM) (AA 50-100) antibody (ABIN730918) Formalin-fixed and paraffin embedded mouse brain tissue labeled with Anti-CD11b/Integ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Integrin alpha M (ITGAM) (AA 50-100) antibody (ABIN730918) Formalin-fixed and paraffin embedded mouse brain tissue labeled with Anti-CD11b/Integ...
Flow Cytometry (FACS) image for anti-Integrin alpha M (ITGAM) (AA 50-100) antibody (ABIN730918) Human U937 cells probed with CD11b/c Polyclonal Antibody, Unconjugated ) (0.2ug) for...
Western Blotting (WB) image for anti-Integrin alpha M (ITGAM) (AA 50-100) antibody (ABIN730918) This image was kindly submitted by Kandy Velazquez from USC School of Medicine. Mouse...