anti-Human CFLAR antibody for Flow Cytometry

Recommended CFLAR Antibody (supplied by: Log in to see )

Antigen
CASP8 and FADD-Like Apoptosis Regulator (CFLAR) Antibodies
  • Clarp1
  • cflar
  • CFLAR
  • FLIP
  • CASH
  • CASP8AP1
  • CLARP
  • Casper
  • FLAME
  • FLAME-1
  • FLAME1
  • I-FLICE
  • MRIT
  • c-FLIP
  • c-FLIPL
  • c-FLIPR
  • c-FLIPS
  • 2310024N18Rik
  • A430105C05Rik
  • Cash
  • ENSMUSG00000072980
  • Flip
  • Gm9845
  • c-Flip
  • CASP8 and FADD-like apoptosis regulator a
  • CASP8 and FADD-like apoptosis regulator
  • cellular FLICE-like inhibitory protein
  • cflara
  • CFLAR
  • cflar
  • Cflar
  • C-FLIP
Epitope
AA 145-174, Center
41
37
24
23
17
15
15
14
10
7
6
6
5
4
4
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
281
136
90
6
2
2
1
1
Host
Rabbit
160
114
23
Clonality
Polyclonal
Conjugate
This CFLAR antibody is un-conjugated
11
8
7
6
6
4
4
4
4
4
4
4
4
4
4
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
256
120
103
42
39
30
28
26
21
8
4
2
2
1
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN653068
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
14.325272 ABIN951489 EIA FACS IHC (p) WB Rabbit Ig AA 152-182, Middle Region Log in to see Polyclonal 1
14.325272 ABIN1724850 FACS IHC ELISA WB Mouse IgG1 AA 100-251 Log in to see 7A3D12 2
14.325272 ABIN4312109 CyTOF ELISA FACS IHC WB Mouse IgG1 Log in to see 7A3D12
14.325272 ABIN1845710 FACS IHC ELISA WB Mouse IgG1 AA 100-251 Log in to see
1 ABIN4312112 ELISA FACS ICC IF IHC IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN4880641 ELISA FACS IHC WB Mouse IgG1 AA 100-251 Log in to see 7A3D12
1 ABIN1823493 FACS IHC (p) ELISA WB Mouse IgG1 AA 100-251 Log in to see 7A3D12
1 ABIN1031381 FACS IF IHC ELISA WB Rabbit N-Term Log in to see Polyclonal
1 ABIN5602449 ELISA FACS IHC WB DyLight 680 Mouse IgG1 AA 100-251 Log in to see 7A3D12
1 ABIN5602450 ELISA FACS IHC WB DyLight 755 Mouse IgG1 AA 100-251 Log in to see 7A3D12
1 ABIN5602448 ELISA FACS IHC WB DyLight 650 Mouse IgG1 AA 100-251 Log in to see 7A3D12
1 ABIN5602445 ELISA FACS IHC WB DyLight 405 Mouse IgG1 AA 100-251 Log in to see 7A3D12
1 ABIN5602451 ELISA FACS IHC FITC Mouse IgG1 AA 100-251 Log in to see 7A3D12
1 ABIN5602453 FACS PerCP Mouse IgG1 AA 100-251 Log in to see 7A3D12
1 ABIN5602447 ELISA FACS IHC WB DyLight 550 Mouse IgG1 AA 100-251 Log in to see 7A3D12
1 ABIN5602454 FACS PE Mouse IgG1 AA 100-251 Log in to see 7A3D12
1 ABIN5602441 ELISA FACS IHC WB Alexa Fluor 700 Mouse IgG1 AA 100-251 Log in to see 7A3D12
1 ABIN5602440 ELISA FACS IHC WB Alexa Fluor 647 Mouse IgG1 AA 100-251 Log in to see 7A3D12
1 ABIN5602439 ELISA FACS IHC WB Alexa Fluor 488 Mouse IgG1 AA 100-251 Log in to see 7A3D12
1 ABIN5602438 ELISA FACS IHC WB Alexa Fluor 405 Mouse IgG1 AA 100-251 Log in to see 7A3D12

General

Antigen CASP8 and FADD-Like Apoptosis Regulator (CFLAR) Antibodies
Epitope AA 145-174, Center
(41), (37), (24), (23), (17), (15), (15), (14), (10), (7), (6), (6), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human
(281), (136), (90), (6), (2), (2), (1), (1)
Host Rabbit
(160), (114), (23)
Clonality (Clone)
Polyclonal   ( )
Conjugate This CFLAR antibody is un-conjugated
(11), (8), (7), (6), (6), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(256), (120), (103), (42), (39), (30), (28), (26), (21), (8), (4), (2), (2), (1), (1), (1), (1)
Pubmed 1 reference available
Supplier Log in to see

Product Details anti-CFLAR Antibody

Target Details CFLAR Application Details Handling ProductDetails: References for anti-CFLAR antibody (ABIN653068) Images
Specificity This CFLAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152~182 amino acids from the Center region of human CFLAR.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen This CFLAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-174 AA from the Central region of human CFLAR.
Clone RB18044
Isotype Ig

Target Details CFLAR

Product Details anti-CFLAR Antibody Application Details Handling ProductDetails: References for anti-CFLAR antibody (ABIN653068) Images back to top
Antigen
Alternative Name CFLAR (CFLAR Antibody Abstract)
Background Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. It acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. It lacks enzymatic (caspase) activity.
Synonyms: CASP8 and FADD-like apoptosis regulator subunit p12, CASP8 and FADD-like apoptosis regulator subunit p43, Usurpin, FADD-like antiapoptotic molecule 1, FLAME-1, Inhibitor of FLICE, I-FLICE, Caspase homolog, CASH, MACH-related inducer of toxicity, MRIT, Caspase-like apoptosis regulatory protein, CLARP, Caspase-eight-related protein, Casper, Cellular FLICE-like inhibitory protein, c-FLIP, CASP8 and FADD-like apoptosis regulator, MRIT, CLARP, CASP8AP1, CASH, CFLAR
Molecular Weight 55344 DA
Gene ID 8837
UniProt O15519
Research Area Apoptosis/Necrosis, Cell Structure
Pathways Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development

Application Details

Product Details anti-CFLAR Antibody Target Details CFLAR Handling ProductDetails: References for anti-CFLAR antibody (ABIN653068) Images back to top
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only

Handling

Product Details anti-CFLAR Antibody Target Details CFLAR Application Details ProductDetails: References for anti-CFLAR antibody (ABIN653068) Images back to top
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

ProductDetails: References for anti-CFLAR antibody (ABIN653068)

Product Details anti-CFLAR Antibody Target Details CFLAR Application Details Handling Images back to top
Background publications

Kim, Pettingell, Jung, Kovacs, Tanzi: "Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease." in: Science (New York, N.Y.), Vol. 277, Issue 5324, pp. 373-6, 1998

Images

Product Details anti-CFLAR Antibody Target Details CFLAR Application Details Handling ProductDetails: References for anti-CFLAR antibody (ABIN653068) back to top
Supplier Images
Western Blotting (WB) image for anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 145-174), (Center) antibody (ABIN653068) Western blot analysis of CFLAR Antibody (Center) (ABIN653068) in HepG2 cell line lysa...
Immunohistochemistry (IHC) image for anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 145-174), (Center) antibody (ABIN653068) Formalin-fixed and paraffin-embedded human skeletal muscle reacted with CFLAR Antibod...
Flow Cytometry (FACS) image for anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 145-174), (Center) antibody (ABIN653068) CFLAR Antibody (Center) (ABIN653068) flow cytometric analysis of k562 cells (bottom h...