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anti-Rat (Rattus) CFLAR antibody for Enzyme Immunoassay

Recommended CFLAR Antibody (supplied by: Log in to see )

Antigen
CASP8 and FADD-Like Apoptosis Regulator (CFLAR) Antibodies
  • Clarp1
  • cflar
  • CFLAR
  • FLIP
  • CASH
  • CASP8AP1
  • CLARP
  • Casper
  • FLAME
  • FLAME-1
  • FLAME1
  • I-FLICE
  • MRIT
  • c-FLIP
  • c-FLIPL
  • c-FLIPR
  • c-FLIPS
  • 2310024N18Rik
  • A430105C05Rik
  • Cash
  • ENSMUSG00000072980
  • Flip
  • Gm9845
  • c-Flip
  • CASP8 and FADD-like apoptosis regulator a
  • CASP8 and FADD-like apoptosis regulator
  • cellular FLICE-like inhibitory protein
  • cflara
  • CFLAR
  • cflar
  • Cflar
  • C-FLIP
Epitope
AA 1-376, N-Term
37
23
23
15
15
15
14
10
10
7
6
6
5
5
4
4
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
249
119
90
6
2
2
1
1
Host
Mouse
160
82
23
Clonality
Monoclonal
Conjugate
This CFLAR antibody is un-conjugated
9
6
5
4
4
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
230
92
75
43
39
30
26
20
14
7
4
2
2
1
1
1
1
Supplier
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Catalog No. ABIN336100
$ 412.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN499846 EIA IF WB Rabbit IgG N-Term Log in to see Polyclonal 4
1 ABIN499848 EIA IF WB Rabbit IgG C-Term Log in to see Polyclonal 4

Top referenced anti-CFLAR antibody for Enzyme Immunoassay

Similar anti-CFLAR Antibodies

Application / Reactivity Mouse (Murine) Rat (Rattus) Human
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies 1 Antibodies
Cytometry by Time of Flight (CyTOF) 1 Antibodies 1 Antibodies
Western Blotting (WB) 215 Antibodies 94 Antibodies 65 Antibodies
SDS-PAGE (SDS) 1 Antibodies 1 Antibodies 1 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Immunoprecipitation (IP) 18 Antibodies 7 Antibodies 4 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 43 Antibodies 16 Antibodies 12 Antibodies
Immunohistochemistry (IHC) 71 Antibodies 20 Antibodies 15 Antibodies

General

Antigen CASP8 and FADD-Like Apoptosis Regulator (CFLAR) Antibodies
Epitope AA 1-376, N-Term
(37), (23), (23), (15), (15), (15), (14), (10), (10), (7), (6), (6), (5), (5), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(249), (119), (90), (6), (2), (2), (1), (1)
Host Mouse
(160), (82), (23)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CFLAR antibody is un-conjugated
(9), (6), (5), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(230), (92), (75), (43), (39), (30), (26), (20), (14), (7), (4), (2), (2), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-CFLAR Antibody

Target Details CFLAR Application Details Handling References for anti-CFLAR Antibody (ABIN336100) Images
Specificity The antibody recognizes FLIP.
Characteristics Synonyms: c-FLIP, CLARP, MRIT, CASH, FLAME-1, CASP8AP1, Usurpin, CASP8 and FADD-like apoptosisregulator, Caspase-eight-related protein, Inhibitor of FLICE, Cellular FLICE-like inhibitoryprotein, Caspase-like apoptosis regulatory protein, MACH-related inducer of toxicity,Caspase homolog, FADD-like antiapoptotic molecule 1
Purification Affinity Chromatography on Protein G
Immunogen Recombinant human FLIP (aa 1-376) purified from E. coli.
Clone 5D8
Isotype IgG3

Target Details CFLAR

Product Details anti-CFLAR Antibody Application Details Handling References for anti-CFLAR Antibody (ABIN336100) Images back to top
Antigen
Alternative Name CFLAR / Casper / I-FLICE (CFLAR Antibody Abstract)
Background FLIP, also known as CASP8 and FADD-like apoptosis regulator (CFLAR), contains two death effector domains (DEDs) and a caspase-like domain. FLIP may play a crucial role between cell survival and cell death pathway in mammalian cells and interacts with adapter protein FADD and Caspase-8 and -10, and potently inhibits apoptosis induced by all known death receptors DR3 (Death Receptor 3), TRAIL-R (TNF-related apoptosis-inducing ligand receptor) and TNFR1 (Tumor Necrosis Factor Receptor 1).Synonyms: CASH, CASP8 and FADD-like apoptosis regulator, CASP8AP1, CLARP, Caspase homolog, Caspase-eight-related protein, Caspase-like apoptosis regulatory protein, Cellular FLICE-like inhibitory protein, FADD-like antiapoptotic molecule 1, FLAME-1, Inhibitor of FLICE, MACH-related inducer of toxicity, MRIT, Usurpin, c-FLIP
Gene ID 8837
UniProt O15519
Pathways Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development

Application Details

Product Details anti-CFLAR Antibody Target Details CFLAR Handling References for anti-CFLAR Antibody (ABIN336100) Images back to top
Application Notes ELISA. Western Blot (1/500-1/1000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-CFLAR Antibody Target Details CFLAR Application Details References for anti-CFLAR Antibody (ABIN336100) Images back to top
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months

References for anti-CFLAR Antibody (ABIN336100)

Product Details anti-CFLAR Antibody Target Details CFLAR Application Details Handling Images back to top
Background publications

Yu, Shi: "FLIP and the death effector domain family." in: Oncogene, Vol. 27, Issue 48, pp. 6216-27, 2008

Du, Guan, Yin, Zhong, Jevnikar: "IL-2-mediated apoptosis of kidney tubular epithelial cells is regulated by the caspase-8 inhibitor c-FLIP." in: Kidney international, Vol. 67, Issue 4, pp. 1397-409, 2005

Images

Product Details anti-CFLAR Antibody Target Details CFLAR Application Details Handling References for anti-CFLAR Antibody (ABIN336100) back to top
Supplier Images
Western Blotting (WB) image for anti-CFLAR antibody (CASP8 and FADD-Like Apoptosis Regulator) (AA 1-376) (ABIN336100) anti-CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (AA 1-376), (N-Term) antibody