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anti-Mouse (Murine) GZMA antibody for Flow Cytometry

Recommended GZMA Antibody (supplied by: Log in to see )

Antigen
Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA) Antibodies
  • AW494114
  • Ctla-3
  • Ctla3
  • CTLA3
  • gzmA
  • GZMA
  • Hf
  • HFSP
  • SE1
  • TSP-1
  • TSP1
Reactivity
Mouse (Murine)
96
31
17
1
1
1
Host
Mouse
55
42
13
Clonality
Monoclonal
Conjugate
This GZMA antibody is conjugated to PE
6
4
4
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
46
33
23
21
17
11
6
5
4
4
3
2
1
1
1
Supplier
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Catalog No. ABIN2662739
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.3068567 ABIN2679995 FACS APC Mouse IgG2b kappa Log in to see GzA-3G8-5 1
0.3068567 ABIN2680001 FACS ICS EFluor 450 Mouse IgG2b kappa Log in to see GzA-3G8-5 1
0.3068567 ABIN2679993 FACS ICS PE Mouse IgG2b kappa Log in to see GzA-3G8-5
0.3068567 ABIN2679997 FACS ICS PE-Cy7 Mouse IgG2b kappa Log in to see GzA-3G8-5
0.3068567 ABIN2679999 FACS ICS PerCP-eFluor® 710 Mouse IgG2b kappa Log in to see GzA-3G8-5
0.0010666476 ABIN2662740 FACS PE Mouse IgG2b kappa Log in to see 3G8-5 4

Top referenced anti-GZMA antibody for Flow Cytometry

Similar anti-GZMA Antibodies

Application / Reactivity Mouse (Murine)
ELISA 5 Antibodies
Flow Cytometry (FACS) 7 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 4 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 4 Antibodies
Intracellular Staining (ICS) 4 Antibodies
Western Blotting (WB) 12 Antibodies

General

Antigen Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA) Antibodies
Reactivity Mouse (Murine)
(96), (31), (17), (1), (1), (1)
Host Mouse
(55), (42), (13)
Clonality (Clone)
Monoclonal   ( )
Conjugate This GZMA antibody is conjugated to PE
(6), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS)
(46), (33), (23), (21), (17), (11), (6), (5), (4), (4), (3), (2), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-GZMA Antibody

Target Details GZMA Application Details Handling References for anti-GZMA Antibody (ABIN2662739) Images
Purification The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Clone 3G8-5
Isotype IgG2b kappa

Target Details GZMA

Product Details anti-GZMA Antibody Application Details Handling References for anti-GZMA Antibody (ABIN2662739) Images back to top
Antigen
Alternative Name Granzyme A (GZMA Antibody Abstract)
Background Granzyme A is a serine protease that is similar to Granzyme B. However, unlike granzyme B, granzyme A is a homodimer. It is expressed in cytotoxic T cells and natural killer cells (NK), but is not essential for induction of apoptosis or DNA fragmentation. Cell death induced by granzyme A is slower and morphologically different than the cell death induced by granzyme B. It plays a crucial role in infection-mediated inflammation as well as immunological responses against viruses, bacteria, and tumor cells.
Research Area Immunology, Innate Immunity, Adaptive Immunity, Apoptosis/Necrosis, Cell/Tissue Markers
Pathways Apoptosis

Application Details

Product Details anti-GZMA Antibody Target Details GZMA Handling References for anti-GZMA Antibody (ABIN2662739) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-GZMA Antibody Target Details GZMA Application Details References for anti-GZMA Antibody (ABIN2662739) Images back to top
Concentration 0.2 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-GZMA Antibody (ABIN2662739)

Product Details anti-GZMA Antibody Target Details GZMA Application Details Handling Images back to top
Background publications

Susanto, Stewart, Voskoboinik, Brasacchio, Hagn, Ellis, Asquith, Sedelies, Bird, Waterhouse, Trapani: "Mouse granzyme A induces a novel death with writhing morphology that is mechanistically distinct from granzyme B-induced apoptosis." in: Cell death and differentiation, Vol. 20, Issue 9, pp. 1183-93, 2013

Fehniger, Cai, Cao, Bredemeyer, Presti, French, Ley: "Acquisition of murine NK cell cytotoxicity requires the translation of a pre-existing pool of granzyme B and perforin mRNAs." in: Immunity, Vol. 26, Issue 6, pp. 798-811, 2007

Ebnet, Hausmann, Lehmann-Grube, Müllbacher, Kopf, Lamers, Simon: "Granzyme A-deficient mice retain potent cell-mediated cytotoxicity." in: The EMBO journal, Vol. 14, Issue 17, pp. 4230-9, 1995

Jenne, Tschopp: "Granzymes, a family of serine proteases released from granules of cytolytic T lymphocytes upon T cell receptor stimulation." in: Immunological reviews, Vol. 103, pp. 53-71, 1988

Images

Product Details anti-GZMA Antibody Target Details GZMA Application Details Handling References for anti-GZMA Antibody (ABIN2662739) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-GZMA antibody (Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3))  (PE) (ABIN2662739) anti-Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA) antibody (PE)
Flow Cytometry (FACS) image for anti-GZMA antibody (Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3))  (PE) (ABIN2662739) anti-Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA) antibody (PE) (Image 2)