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Browse our anti-PYGL (PYGL) Antibodies

Full name:
anti-phosphorylase, Glycogen, Liver Antibodies (PYGL)
On www.antibodies-online.com are 83 phosphorylase, Glycogen, Liver (PYGL) Antibodies from 15 different suppliers available. Additionally we are shipping PYGL Kits (40) and PYGL Proteins (19) and many more products for this protein. A total of 143 PYGL products are currently listed.
Synonyms:
GSD6, zgc:66314

Most Popular Reactivities for anti-PYGL (PYGL) Antibodies

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anti-Mouse (Murine) PYGL Antibodies:

anti-Human PYGL Antibodies:

anti-Rat (Rattus) PYGL Antibodies:

All available anti-PYGL Antibodies

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Top referenced anti-PYGL Antibodies

  1. Human Polyclonal PYGL Primary Antibody for ICC, IF - ABIN4348737 : Nogales-Gadea, Mormeneo, García-Consuegra, Rubio, Orozco, Arenas, Martín, Lucia, Gómez-Foix, Martí, Andreu: Expression of glycogen phosphorylase isoforms in cultured muscle from patients with McArdle's disease carrying the p.R771PfsX33 PYGM mutation. in PLoS ONE 2010 (PubMed)

More Antibodies against PYGL Interaction Partners

Mouse (Murine) phosphorylase, Glycogen, Liver (PYGL) interaction partners

  1. The in vivo consequences of disrupting the G(L)-phosphorylase a interaction, using a mouse model containing a Tyr284Phe substitution in the phosphorylase a-binding region of the hepatic glycogen (show GYS1 Antibodies)-associated protein phosphatase-1 (show PPP1CB Antibodies) protein, is reported.

Human phosphorylase, Glycogen, Liver (PYGL) interaction partners

  1. Susceptibility to excessive liver glycogen (show GYS1 Antibodies) storage in patients with type 1 diabetes.

  2. Deficiency of liver glycogen phosphorylase is predominantly the result of missense mutations affecting enzyme activity. There are no common mutations and the severity of clinical symptoms varies significantly.

Pig (Porcine) phosphorylase, Glycogen, Liver (PYGL) interaction partners

  1. 4-alpha-glucanotransferase action of porcine liver GDE (show AGL Antibodies) on four 6(4)-O-alpha-maltooligosyl-pyridylamino(PA)-maltooctaoses, in the presence or absence of an acceptor, maltohexaose, was examined.

PYGL Antigen Profile

Antigen Summary

This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively. The liver isozyme serves the glycemic demands of the body in general while the brain and muscle isozymes supply just those tissues. In glycogen storage disease type VI, also known as Hers disease, mutations in liver glycogen phosphorylase inhibit the conversion of glycogen to glucose and results in moderate hypoglycemia, mild ketosis, growth retardation and hepatomegaly. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with PYGL

  • phosphorylase, glycogen, liver (PYGL) antibody
  • phosphorylase, glycogen; liver (Hers disease, glycogen storage disease type VI) (pygl) antibody
  • phosphorylase, glycogen, liver (pygl) antibody
  • liver glycogen phosphorylase (Pygl) antibody
  • phosphorylase, glycogen, liver (Pygl) antibody
  • GSD6 antibody
  • zgc:66314 antibody

Protein level used designations for PYGL

glycogen phosphorylase, liver form , liver glycogen phosphorylase , phosphorylase, glycogen; liver (Hers disease, glycogen storage disease type VI) , glycogen storage disease type VI-related protein , phosphorylase, glycogen; liver

GENE ID SPECIES
100066726 Equus caballus
378909 Gallus gallus
493916 Danio rerio
494832 Xenopus laevis
706853 Macaca mulatta
742309 Pan troglodytes
110095 Mus musculus
5836 Homo sapiens
403738 Canis lupus familiaris
100141306 Sus scrofa
505472 Bos taurus
64035 Rattus norvegicus
554320 Ovis aries
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