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anti-Mouse (Murine) Occludin Antibodies:
anti-Rat (Rattus) Occludin Antibodies:
anti-Human Occludin Antibodies:
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Human Polyclonal Occludin Primary Antibody for IF (p), IHC (p) - ABIN687337
Gu, Xue, Wei, Zhang, Li: Calcium-activated potassium channel activator down-regulated the expression of tight junction protein in brain tumor model in rats. in Neuroscience letters 2011
Show all 5 Pubmed References
Dog (Canine) Monoclonal Occludin Primary Antibody for IF, WB - ABIN968360
Ando-Akatsuka, Saitou, Hirase, Kishi, Sakakibara, Itoh, Yonemura, Furuse, Tsukita: Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues. in The Journal of cell biology 1996
Show all 3 Pubmed References
Dog (Canine) Monoclonal Occludin Primary Antibody for IF, WB - ABIN968361
Bolton, Anthony, Perry: Loss of the tight junction proteins occludin and zonula occludens-1 from cerebral vascular endothelium during neutrophil-induced blood-brain barrier breakdown in vivo. in Neuroscience 1998
Show all 3 Pubmed References
Dog (Canine) Monoclonal Occludin Primary Antibody for IF, IHC (p) - ABIN337048
Krueger, Härtig, Reichenbach, Bechmann, Michalski: Blood-brain barrier breakdown after embolic stroke in rats occurs without ultrastructural evidence for disrupting tight junctions. in PLoS ONE 2013
Cow (Bovine) Polyclonal Occludin Primary Antibody for WB - ABIN2775620
Shen, Weber, Turner: The tight junction protein complex undergoes rapid and continuous molecular remodeling at steady state. in The Journal of cell biology 2008
Show all 2 Pubmed References
Human Polyclonal Occludin Primary Antibody for IHC (fro), IF - ABIN2192203
Van Itallie, Anderson: Occludin confers adhesiveness when expressed in fibroblasts. in Journal of cell science 1997
Human Polyclonal Occludin Primary Antibody for ELISA, ICC - ABIN4341292
Liu, Xu, Ji, Liu, Mo, Tollerud, Gu, Zhang: Sublethal effects of zinc oxide nanoparticles on male reproductive cells. in Toxicology in vitro : an international journal published in association with BIBRA 2016
Endothelial cellsTLR4 strongly regulates retinal vessel permeability by reducing expression of occludin and zonula occludens 1 (show TJP1 Antibodies).
The zinc sensing receptor, ZnR/GPR39 (show GPR39 Antibodies), triggers intracellular Ca(2 (show CA2 Antibodies)+) signalling in colonocytes thereby inducing occludin expression. Moreover, ZnR/GPR39 (show GPR39 Antibodies) is essential for epithelial barrier recovery in the dextran sodium sulfate (DSS (show PMP22 Antibodies)) ulcerative colitis model.
Occludin expression by epidermal gammadelta T cells upon activation in response to epidermal stress allows them to move, which could be important for augmentation of immune responses via collaboration with other cells.
Intracellular zinc has an essential role in the maintenance of the intestinal epithelial tight junction barrier through regulation of occludin proteolysis and claudin-3 (show CLDN3 Antibodies) transcription.
miR (show MLXIP Antibodies)-429 could down-regulate the expression of Ocln by targeting the Ocln 3'-UTR (show UTS2R Antibodies), which impaired intestinal barrier function in diabetes mellitus mice.
STAT3 activation downregulates the ZO-1 and occludin levels and increases the endothelial permeability through the induction of VEGF production in retinal endothelial cells.
Tricellulin (show MARVELD2 Antibodies) is a specific redox sensor and sealing element at 3-cell contacts and may compensate as a redox mediator for occludin loss at 2-cell contacts in vivo and in vitro.
These findings provide evidence for occludin playing a role in the invasion of Toxoplasma gondii in small intestinal epithelial cells.
occludin deficiency increases susceptibility to ethanol-induced colonic mucosal barrier dysfunction and liver damage in mice.
PHD3 (show EGLN3 Antibodies) protects intestinal epithelial barrier function and reveal a hydroxylase-independent function of PHD3 (show EGLN3 Antibodies) in stabilizing occludin
ZO-1 (show TJP1 Antibodies) and occludin are expressed in oocytes and preimplantation embryos, and that ZO-1alpha+ is transcribed by zygotic gene activation and translated from early blastocysts with prominent increase of occludin at the blastocyst stage.
ADMA has potent adverse effects on cell proliferation, intracellular ROS (show ROS1 Antibodies) generation, cell permeability, levels of ICAM-1 (show ICAM1 Antibodies), and the tight-junction protein occludin
the presence of occludin at the membrane is dependent in part on calcium-sensitive signaling cascades
cyclic strain modulates both the expression and phosphorylation state of occludin and ZO-1 (show TJP1 Antibodies) in vascular endothelial cells, with putative consequences for endothelial tight junction assembly and barrier integrity
These data demonstrate a novel mechanism of VEGF (show VEGFA Antibodies)-induced occludin phosphorylation and ubiquitination that contributes to TJ trafficking and subsequent vascular permeability.
Glutamine (show GFPT1 Antibodies) increased claudin-1 (show CLDN7 Antibodies) expression in the colonic mucosa of patients with irritable bowel syndrome. In contrast, occludin expression was not significantly modified by glutamine (show GFPT1 Antibodies).
Viral infectivity was significantly reduced by miR (show MLXIP Antibodies)-200c but enhanced by miR (show MLXIP Antibodies)-122.
The mechanism of transition from nondifferentiated to differentiated states in HepaRG cells was studed by proteomics. Two key factors (MMP-14 (show MMP14 Antibodies) and OCLN) were validated by qRT-PCR and Western blot.
Data suggest that long noncoding RNA PlncRNA1 and microRNA miR (show MLXIP Antibodies)-34c bound together to regulate the expressions of MAZ (show MAZ Antibodies), ZO-1 (show TJP1 Antibodies) and occludin.
Study provides evidence that occludin contributes to the regulation of size-reductive proliferation and epithelial cell maturation in a phosphorylation-dependent manner.
Report shows that silencing MARCH3 (show MARCH3 Antibodies) protects the endothelial barrier and upregulates OCLN in MARCH3 (show MARCH3 Antibodies)-depleted cells. MARCH3 (show MARCH3 Antibodies) silencing results in the strengthening of cell-cell contacts and inactivates FoxO1 (show FOXO1 Antibodies).
Downregulation of OCLN is associated with clear cell renal cell carcinoma (show MOK Antibodies).
This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.
, tight-junction protein
, thiopurine methyltransferase
, tight junction protein occludin