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anti-Human TTC5 Antibodies:
anti-Mouse (Murine) TTC5 Antibodies:
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Cow (Bovine) Polyclonal TTC5 Primary Antibody for WB - ABIN2783601
Demonacos, Krstic-Demonacos, La Thangue: A TPR motif cofactor contributes to p300 activity in the p53 response. in Molecular cell 2001
Human Polyclonal TTC5 Primary Antibody for EIA, IHC (p) - ABIN501091
Blatch, Lässle: The tetratricopeptide repeat: a structural motif mediating protein-protein interactions. in BioEssays : news and reviews in molecular, cellular and developmental biology 1999
Human TTC5, a novel tetratricopeptide repeat domain containing gene, activates p53 (show TP53 Antibodies) and inhibits AP-1 (show FOSB Antibodies) pathway.
TTC5 and EP300 (show EP300 Antibodies) cooperate to prevent excessive accumulation of MYC (show MYC Antibodies) in AML (show RUNX1 Antibodies) cells and their sensitization to cell death.
TTC5 is a novel cofactor regulating GR function in a stress-dependent manner.
Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity).
tetratricopeptide repeat domain 5
, tetratricopeptide repeat protein 5
, tetratricopeptide repeat protein 5-like
, TPR repeat protein 5
, stress-responsive activator of p300