Browse our Kallikrein 1 Proteins (KLK1)

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Kallikrein 1 Proteins (KLK1)
On are 32 Kallikrein 1 (KLK1) Proteins from 14 different suppliers available. Additionally we are shipping Kallikrein 1 Antibodies (124) and Kallikrein 1 Kits (50) and many more products for this protein. A total of 215 Kallikrein 1 products are currently listed.
0610007D04Rik, hK1, KAL, kallikrein, kallistatin, Klk1b3, Klk1b6, Klk1c1, Klk6, KLKR, KLST, KST, mGk-6, Ngfg, PI-4, PI4, rGK-1, rK-1
list all proteins Gene Name GeneID UniProt
KLK1 3816 P06870
KLK1 16612 P15947
KLK1 24594 P00758

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Kallikrein 1 Proteins (KLK1) by Origin

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Top referenced Kallikrein 1 Proteins

  1. Mouse (Murine) Kallikrein 1 Protein expressed in Human Cells - ABIN3216408 : Henttu, Lukkarinen, Vihko: Expression of the gene coding for human prostate-specific antigen and related hGK-1 in benign and malignant tumors of the human prostate. in International journal of cancer. Journal international du cancer 1990 (PubMed)
    Show all 3 references for 3216408

  2. Human Kallikrein 1 Protein expressed in HEK-293 Cells - ABIN2181428 : Chen, Murray, Chai, Chao, Chao: Molecular cloning and characterization of a novel kallikrein transcript in colon and its distribution in human tissues. in Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1995 (PubMed)
    Show all 3 references for 2181428

  3. Human Kallikrein 1 Protein expressed in Human Cells - ABIN2002789 : Clements, Hooper, Dong, Harvey: The expanded human kallikrein (KLK) gene family: genomic organisation, tissue-specific expression and potential functions. in Biological chemistry 2001 (PubMed)
    Show all 3 references for 2002789

  4. Human Kallikrein 1 Protein expressed in Escherichia coli (E. coli) - ABIN1098427 : Lu, Lin, Chao, Chao: Human urinary kallikrein. Complete amino acid sequence and sites of glycosylation. in International journal of peptide and protein research 1989 (PubMed)
    Show all 2 references for 1098427

  5. Human Kallikrein 1 Protein expressed in Wheat germ - ABIN1308832 : Kahn, Hellmark, Leeb-Lundberg, Akbari, Todiras, Olofsson, Wieslander, Christensson, Westman, Bader, Müller-Esterl, Karpman: Neutrophil-derived proteinase 3 induces kallikrein-independent release of a novel vasoactive kinin. in Journal of immunology (Baltimore, Md. : 1950) 2009 (PubMed)

More Proteins for Kallikrein 1 Interaction Partners

Human Kallikrein 1 (KLK1) interaction partners

  1. Our results indicate that during severe sepsis and septic shock, a decrease in plasma concentrations of kallistatin (show SERPINA4 Proteins) reflects increased severity and poorer outcome of disease.

  2. data suggest that overexpression of kallistatin (show SERPINA4 Proteins) interferes with lymphopoiesis, ultimately impacting the level of circulating CD19 (show CD19 Proteins)(+) B lymphocytes.

  3. Recognition of anti-tumor necrosis factor-alpha (TNF-alpha) or Kallikrein Inhibitor may lead to therapeutics to enhance existing treatments for patients who do not respond to anti-vascular endothelial growth factor (VEGF) therapies.

  4. increasing the serum levels of AngII increased the risk of acute myocardial infarction (AMI (show CFD Proteins)); the risk of AMI (show CFD Proteins) increased when the serum levels of AngII and KLK1 simultaneously increased; individuals with the combined genotypes of ACE (show ACE Proteins) DD and KLK1 GG showed increased risk of AMI (show CFD Proteins) compared with those with the combined genotypes of ACE (show ACE Proteins) II and KLK1 AA

  5. The rs5516 G allele of KLK1 was significantly associated with aortic aneurysm

  6. Kallistatin (show SERPINA4 Proteins) levels were correlated with some markers of systemic inflammation in the HIV population.

  7. KLK1 rs5516 SNP is not related to the incidence of Alzheimer's disease in a Hunan Han Chinese population.

  8. TK promoted cell survival and beta-catenin (show CTNNB1 Proteins) degradation in serum-starved SH-SY5Y cells via increasing autophagy.

  9. Increased kallistatin (show SERPINA4 Proteins) levels in type 1 diabetes and its relation with carotid intima media thickness may reflect vascular dysfunction and suggest a link between micro- and macro-angiopathy.

  10. reveal novel mechanisms of kallistatin (show SERPINA4 Proteins) in inducing apoptosis and autophagy in breast cancer cells

Mouse (Murine) Kallikrein 1 (KLK1) interaction partners

  1. Polypeptides identified based on immunorecognition by autoantibodies in sera from IQI/Jic mice affected with autoimmune disease (>12 weeks of age) were tissue kallikrein (Klk)-1 and -13 and were cross-reactive to the autoantibodies.

  2. Protective effects of Tissue kallikrein gene transfer on ischemic diseases.

  3. TK, like several other proteases, can activate ENaC (show SCNN1A Proteins) in the kidney and the colon.

  4. Tissue kallikrein and kinins do not influence the trophicity of kidneys, the synthesis and secretion of renin (show REN Proteins), blood pressure increase, and cardiac remodeling due to renin (show REN Proteins) angiotensin system activation.

  5. tissue kallikrein knockout mice had a significant two-fold increase in albuminuria

  6. The study suggests that kallikrein plays an antihypertensive role in hyperaldosteronism.

  7. These data do not support a role for the TK-kinin system, protective or deleterious, in the development of insulin (show INS Proteins) resistance and diabetes.

  8. Lower excretion of active renin (show REN Proteins) and prorenin in TK(-/-) compared to TK(+/+) suggest coordinated regulation of the two proteins in their participation to collecting duct function.

  9. Plasma kallikrein (show KLKB1 Proteins)-deficient mice challenged with transient middle cerebral artery occlusion developed significantly smaller brain infarctions.

  10. The data of this study presented support the conclusion that Klk6 is an important participant in the immunopathogenic events that drive TMEV-IDD (show DGS2 Proteins) at acute through early chronic time points.

Kallikrein 1 (KLK1) Protein Profile

Protein Summary

Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.

Alternative names and synonyms associated with Kallikrein 1 (KLK1)

  • kallikrein 1 (klk1)
  • kallikrein 1 (KLK1)
  • kallikrein 1 (Klk1)
  • kallikrein 1 (LOC100101620)
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 (SERPINA4)
  • 0610007D04Rik protein
  • hK1 protein
  • KAL protein
  • kallikrein protein
  • kallistatin protein
  • Klk1b3 protein
  • Klk1b6 protein
  • Klk1c1 protein
  • Klk6 protein
  • KLKR protein
  • KLST protein
  • KST protein
  • mGk-6 protein
  • Ngfg protein
  • PI-4 protein
  • PI4 protein
  • rGK-1 protein
  • rK-1 protein

Protein level used designations for Kallikrein 1 Proteins (KLK1)

kallikrein 1 , glandular kallikrein 1 , kallikrein 1, renal/pancreas/salivary , kallikrein serine protease 1 , kallikrein-1 , kidney/pancreas/salivary gland kallikrein , tissue kallikrein , KAL-B , glandular kallikrein K1 , kallikrein 6 , kallikrein renal/pancreas/salivary , renal kallikrein , tissue kallikrein-6 , true tissue kallikrein , glandular kallikrein , PS kallikrein , gamma-NGF , kallikrein 1-related peptidase b3 , nerve growth factor gamma chain , nerve growth factor gamma polypeptide , pancreatic kallikrein , kallikrein inhibitor , kallistatin , peptidase inhibitor 4 , protease inhibitor 4 (kallistatin) , serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 , serpin A4

495211 Xenopus laevis
3816 Homo sapiens
16612 Mus musculus
100101620 Oryctolagus cuniculus
403942 Canis lupus familiaris
431673 Sus scrofa
24594 Rattus norvegicus
493738 Bos taurus
100048991 Ovis aries
5267 Homo sapiens
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