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Kallikrein 1 Protein (KLK1) (His tag)

KLK1 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318695
  • Target See all Kallikrein 1 (KLK1) Proteins
    Kallikrein 1 (KLK1)
    Protein Type
    Recombinant
    Origin
    • 11
    • 6
    • 3
    • 1
    Human
    Source
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Human Cells
    Purification tag / Conjugate
    This Kallikrein 1 protein is labelled with His tag.
    Purpose
    Recombinant Human Kallikrein 1/KLK1 Protein (His Tag)
    Sequence
    Pro19-Ser262
    Characteristics
    Recombinant Human Kallikrein 1 is produced by our Mammalian expression system and the target gene encoding Pro19-Ser262 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product KLK1 Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 2 mM CaCl2, pH 8.0.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    Kallikrein 1 (KLK1)
    Alternative Name
    Kallikrein 1/KLK1 (KLK1 Products)
    Synonyms
    KLKR Protein, Klk6 Protein, hK1 Protein, klkr Protein, kallikrein Protein, 0610007D04Rik Protein, Kal Protein, Klk1b6 Protein, mGk-6 Protein, kallikrein 1 Protein, kallikrein 1 L homeolog Protein, KLK1 Protein, klk1.L Protein, LOC100101620 Protein, Klk1 Protein
    Background

    Background: Kallikrein-1 (KLK1) is a member of human tissue Kallikrein family. Human KLK1 precursor contains a singal peptide (residues 1 to 18), a short pro peptide (residues 19 to 24) and a mature chain (residues 25 to 262). The function of KLK1 is to cleave Kininogen in order to release the vasoactive Kinin peptide (Lysyl-Bradykinin or Bradykinin). The Kinin peptide controls blood pressure reduction, vasodilation, smooth muscle relaxation and contraction, pain induction and inflammation. KLK1 also plays a role in angiogensis and tumorigenesis.

    Synonym: Kallikrein-1, Kidney/Pancreas/Salivary Gland Kallikrein, Tissue Kallikrein, KLK1

    Molecular Weight
    28.2 kDa
    UniProt
    P06870
    Pathways
    Complement System
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