Browse our Kallikrein 5 Proteins (KLK5)

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Kallikrein 5 Proteins (KLK5)
On are 11 Kallikrein 5 (KLK5) Proteins from 7 different suppliers available. Additionally we are shipping Kallikrein 5 Antibodies (87) and Kallikrein 5 Kits (34) and many more products for this protein. A total of 137 Kallikrein 5 products are currently listed.
1110030O19Rik, KAL, KALA, KLK-L2, Klk1, Klk5, KLKL2, RATKALA, SCTE
list all proteins Gene Name GeneID UniProt
Rat KLK5 KLK5 687873  
KLK5 68668  
KLK5 25818 Q9Y337

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Kallikrein 5 Proteins (KLK5) by Origin

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Top referenced Kallikrein 5 Proteins

  1. Human Kallikrein 5 Protein expressed in Escherichia coli (E. coli) - ABIN1098660 : Clements, Hooper, Dong, Harvey: The expanded human kallikrein (KLK) gene family: genomic organisation, tissue-specific expression and potential functions. in Biological chemistry 2001 (PubMed)
    Show all 2 references for 1098660

More Proteins for Kallikrein 5 Interaction Partners

Mouse (Murine) Kallikrein 5 (KLK5) interaction partners

  1. Ablation of KLK5 is not sufficient to rescue the lethal effect of LEKTI-deficiency. Double deficiency of both KLK5 and KLK7 completely rescues Netherton Syndrome-like phenotype.

  2. the pruritogenic action of KLK5 may be primarily mediated by PAR2 (show F2RL1 Proteins) receptors

  3. findings illustrate the crucial role of protease regulation in skin homeostasis and inflammation, and establish KLK5 inhibition as a major therapeutic target for NS

  4. The cloning and characteriazation of recombinant Klk5 is reported.

Human Kallikrein 5 (KLK5) interaction partners

  1. It may be considered that circulating kallikrein 5 is down-regulated in chronic spontaneous urticaria patients, however its potential role and the possible underlying mechanism are unknown.

  2. Thus, these findings point to the involvement of KLK5 in the proteolytic activation and spread of seasonal influenza viruses in humans.

  3. The results of the present study indicated that the mRNA and protein expression levels of KLK5 were significantly upregulated in CRC (show CALR Proteins) tissues and sera, and were associated with an advanced tumor stage.

  4. the expression level of hK5 in tumor stromal cells is a promising biomarker for poor prognosis in TNBC.

  5. This report demonstrates that concurrent loss of KLK5 and KLK7 (show KLK7 Proteins) associates with a poor clinical outcome in Oral Squamous-Cell Carcinoma and could therefore serve as prognostic marker in this disease.

  6. Low KLK5 expression is associated with breast cancer.

  7. KLK5 is an important contributor to the Netherton syndrome proteolytic cascade.

  8. Data indicate that the KLK5 SNP rs268908 was associated with an increased risk of prostate cancer.

  9. Kallikrein 5 and kallikrein 12 (show KLK12 Proteins) cleave human influenza hemagglutinins and activate thrombolytic zymogens.

  10. KLK5 is required for biochemical processing of profilaggrin (show FLG Proteins) in human skin.

Kallikrein 5 (KLK5) Protein Profile

Protein Summary

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein.

Alternative names and synonyms associated with Kallikrein 5 (KLK5)

  • similar to kallikrein 5 preproprotein (LOC687873)
  • kallikrein 5-like (Klk5l)
  • kallikrein related-peptidase 5 (Klk5)
  • kallikrein-related peptidase 5 (KLK5)
  • 1110030O19Rik protein
  • KAL protein
  • KALA protein
  • KLK-L2 protein
  • Klk1 protein
  • Klk5 protein
  • KLKL2 protein
  • RATKALA protein
  • SCTE protein

Protein level used designations for Kallikrein 5 Proteins (KLK5)

Kallikrein 1 renal/pancreas/salivary , kallikrein 5 , kallikrein-5 , kallikrein-like protein 2 , stratum corneum tryptic enzyme

687873 Rattus norvegicus
408211 Rattus norvegicus
690603 Rattus norvegicus
68668 Mus musculus
25818 Homo sapiens
484353 Canis lupus familiaris
617418 Bos taurus
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