anti-Dog (Canine) Prothrombin antibody for Immunohistochemistry

Recommended Prothrombin Antibody (supplied by: Log in to see )

Antigen
Coagulation Factor II (thrombin) (F2) Antibodies
  • zgc:66319
  • wu:fb57c10
  • wu:fd42e09
  • wu:fd59d01
  • Cf-2
  • Cf2
  • FII
  • thrombin
  • PT
  • RPRGL2
  • THPH1
  • prothrombin
  • AA959438
  • AI255193
  • AI327365
  • C1sa
  • HTRA
  • HTRA1
  • F2
  • coagulation factor II (thrombin)
  • cell division cycle 34
  • chymase 1, mast cell
  • coagulation factor II
  • complement component 1, s subcomponent
  • HtrA serine peptidase 1
  • HtrA serine peptidase 2
  • melanoma antigen family B, 17-like
  • prothrombin-like
  • serine protease
  • THROMBIN protein
  • f2
  • F2
  • Cdc34
  • CMA1
  • C1s
  • Htra1
  • HTRA2
  • LOC783975
  • LOC100856539
  • HTRA
  • THROMBIN
Epitope
Middle Region
8
8
7
6
6
5
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rat (Rattus), Sheep (Ovine), Zebrafish
149
68
35
7
7
4
1
1
1
1
Host
Rabbit
84
63
56
8
6
4
2
Clonality
Polyclonal
Conjugate
This Prothrombin antibody is un-conjugated
23
12
12
5
4
4
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
143
108
38
20
19
16
15
14
14
13
11
8
6
3
3
2
1
1
1
1
1
1
1
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Catalog No. ABIN2776976
$ 289.00
Plus shipping costs $45.00

General

Antigen Coagulation Factor II (thrombin) (F2) Antibodies
Epitope Middle Region
(8), (8), (7), (6), (6), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rat (Rattus), Sheep (Ovine), Zebrafish
(149), (68), (35), (7), (7), (4), (1), (1), (1), (1)
Host Rabbit
(84), (63), (56), (8), (6), (4), (2)
Clonality
Polyclonal
Conjugate This Prothrombin antibody is un-conjugated
(23), (12), (12), (5), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(143), (108), (38), (20), (19), (16), (15), (14), (14), (13), (11), (8), (6), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-Prothrombin Antibody

Target Details Prothrombin Application Details Handling ProductDetails: References for anti-Prothrombin antibody (ABIN2776976) Images
Blocking Peptide Blocking peptide for this product available: ABIN976548
Sequence ISDRWVLTAA HCLLYPPWDK NFTENDLLVR IGKHSRTRYE RNIEKISMLE
Predicted Reactivity Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 77%
Characteristics This is a rabbit polyclonal antibody against F2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human F2

Target Details Prothrombin

Product Details anti-Prothrombin Antibody Application Details Handling ProductDetails: References for anti-Prothrombin antibody (ABIN2776976) Images back to top
Antigen
Alternative Name F2 (F2 Antibody Abstract)
Background Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life.Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PT
Protein Interaction Partner: ST13, FN1, DDIT3, ALB, F11, PROZ, ITGA2B, SERPING1, HGFAC, AKR7A2, CPB2, F2RL3, F2RL2, SERPINA5, SERPINB8, AANAT, F2RL1, F9, F8, GP1BA, KNG1, F5, C6, PLAU, THBS1, THBD, F2R, SERPINE2, F2, PROS1, AMBP, PROC, GP5, SERPINE1, SERPINB6, SPP1, IGFBP5, IGFBP3, S
Protein Size: 622
Molecular Weight 70 kDa
Gene ID 2147
NCBI Accession NM_000506, NP_000497
UniProt P00734
Pathways Complement System, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling

Application Details

Product Details anti-Prothrombin Antibody Target Details Prothrombin Handling ProductDetails: References for anti-Prothrombin antibody (ABIN2776976) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 622 AA

Restrictions For Research Use only

Handling

Product Details anti-Prothrombin Antibody Target Details Prothrombin Application Details ProductDetails: References for anti-Prothrombin antibody (ABIN2776976) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

ProductDetails: References for anti-Prothrombin antibody (ABIN2776976)

Product Details anti-Prothrombin Antibody Target Details Prothrombin Application Details Handling Images back to top
Background publications

Rossi, Za, Ciminello, Leone, De Stefano: "The risk of symptomatic pulmonary embolism due to proximal deep venous thrombosis differs in patients with different types of inherited thrombophilia." in: Thrombosis and haemostasis, Vol. 99, Issue 6, pp. 1030-4, 2008

Images

Product Details anti-Prothrombin Antibody Target Details Prothrombin Application Details Handling ProductDetails: References for anti-Prothrombin antibody (ABIN2776976) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Coagulation Factor II (thrombin) (F2) (Middle Region) antibody (ABIN2776976) anti-Coagulation Factor II (thrombin) (F2) (Middle Region) antibody