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Browse our Minichromosome Maintenance Complex Component 6 Proteins (MCM6)

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Minichromosome Maintenance Complex Component 6 Proteins (MCM6)
On www.antibodies-online.com are 5 Minichromosome Maintenance Complex Component 6 (MCM6) Proteins from 3 different suppliers available. Additionally we are shipping Minichromosome Maintenance Complex Component 6 Antibodies (80) and Minichromosome Maintenance Complex Component 6 Kits (1) and many more products for this protein. A total of 90 Minichromosome Maintenance Complex Component 6 products are currently listed.
Synonyms:
ASP-l1, CG4039, D1Wsu22e, Dmel\\CG4039, DmeMCM6, DmMCM6, fs(1)K1214, MCG40308, mcm6, Mcmd6, mis5, mmcm6, P105MCM
list all proteins Gene Name GeneID UniProt
MCM6 4175 Q14566
Rat MCM6 MCM6 29685  
MCM6 17219 P97311

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Minichromosome Maintenance Complex Component 6 Proteins (MCM6) by Origin

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Top referenced Minichromosome Maintenance Complex Component 6 Proteins

  1. Human MCM6 Protein expressed in Wheat germ - ABIN1310559 : Henderson, Hall, Prpic, Hessling, Parker, Sampson, Simkins, Brough, Dixon, Lenz, Knapp, Murphy, Taylor, Fischer, Malinowski: The selection and characterization of antibodies to minichromosome maintenance proteins that highlight cervical dysplasia. in Journal of immunological methods 2011 (PubMed)

More Proteins for Minichromosome Maintenance Complex Component 6 Interaction Partners

Human Minichromosome Maintenance Complex Component 6 (MCM6) interaction partners

  1. Methyl(R217)HuR (show ELAVL1 Proteins) and MCM6 are inversely correlated and are prognostic markers in non small cell lung carcinoma

  2. Purified MCM4 (show MCM4 Proteins)/6/7 complex containing the G364R MCM4 (show MCM4 Proteins) exhibited similar levels of single-stranded DNA binding and ATPase activities to the complex containing wild-type MCM4 (show MCM4 Proteins)

  3. Report presence of homozygous--13910CC genetic variant in the MCM-6 gene upstream from the lactase (show LCT Proteins) gene in lactose intolerant patients treated with lactose-restricted diet.

  4. Mcm2-7 (show MCM2 Proteins) loads onto origins during initiation as a double hexamer, yet does not act as a double-stranded DNA pump during elongation.

  5. The subtype and MCM6 protein expression in craniopharyngiomas are related to the prognosis of tumor.

  6. the molecular mechanism of Mcm2-7 (show MCM2 Proteins) chromatin loading and prereplicative complex assembly.

  7. Data show that cells subjected to chronic hypoxia the replicative restart was inhibited along with numerous replication factors including MCM6 and RPA (show RPA1 Proteins), and cells reoxygenated after acute hypoxia underwent rapid p53 (show TP53 Proteins)-dependent apoptosis.

  8. It was found that the MCM6 label index (LI) was significantly higher in adamantine epithelioma than squamous papillary tumor, and in both primary tumor subtypes the LIs of tumors with recurrence were higher than those without recurrence.

Mouse (Murine) Minichromosome Maintenance Complex Component 6 (MCM6) interaction partners

  1. role of subunits in dna helicase activity

  2. Substrate preference and helicase actions of mouse MCM4/6/7 helicase complexes.

  3. Accumulation and dynamics of Mcm6 are described during oogenesis and the first embryonic cell cycle.

  4. DNA binding and helicase activities of Mcm4 (show MCM4 Proteins)/6/7 are significantly stimulated by Cdt1 (show CDT1 Proteins)

Minichromosome Maintenance Complex Component 6 (MCM6) Protein Profile

Protein Summary

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. Single nucleotide polymorphisms in the intron regions of this gene are associated with differential transcriptional activation of the promoter of the neighboring lactase gene and, thereby, influence lactose intolerance in early adulthood.

Alternative names and synonyms associated with Minichromosome Maintenance Complex Component 6 (MCM6)

  • Minichromosome maintenance 6 (Mcm6)
  • DNA replication licensing factor MCM6 (TP02_0113)
  • DNA replication licensing factor MCM6 (PVX_114735)
  • DNA replication licensing factor MCM6 (CMU_027970)
  • minichromosome maintenance complex component 6 (MCM6)
  • minichromosome maintenance complex component 6 (Mcm6)
  • minichromosome maintenance complex component 6 (mcm6)
  • minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) (Mcm6)
  • Protein MCM-6 (mcm-6)
  • ASP-l1 protein
  • CG4039 protein
  • D1Wsu22e protein
  • Dmel\\CG4039 protein
  • DmeMCM6 protein
  • DmMCM6 protein
  • fs(1)K1214 protein
  • MCG40308 protein
  • mcm6 protein
  • Mcmd6 protein
  • mis5 protein
  • mmcm6 protein
  • P105MCM protein

Protein level used designations for MCM6

CG4039-PA , Mcm6-PA , female sterile(1)K1214 , minichromosome maintenance 6 , DNA replication licensing factor MCM6 , MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) , minichromosome maintenance deficient (mis5, S. pombe) 6 , minichromosome maintenance deficient 6 homolog , intestinal DNA replication protein , mini chromosome maintenance deficient 6 , minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) , maternal DNA replication licensing factor mcm6 , maternal minichromosome maintenance protein 6 , mis5p , xMCM6 , mis5 homolog

GENE ID SPECIES
31603 Drosophila melanogaster
3501563 Theileria parva strain Muguga
5475634 Plasmodium vivax Sal-1
6994823 Cryptosporidium muris RN66
4175 Homo sapiens
476131 Canis lupus familiaris
517812 Bos taurus
29685 Rattus norvegicus
398071 Xenopus laevis
17219 Mus musculus
176385 Caenorhabditis elegans
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