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Browse our anti-Amyloid beta (A4) Precursor-Like Protein 2 (APLP2) Antibodies

Full name:
anti-Amyloid beta (A4) Precursor-Like Protein 2 Antibodies (APLP2)
On www.antibodies-online.com are 91 Amyloid beta (A4) Precursor-Like Protein 2 (APLP2) Antibodies from 20 different suppliers available. Additionally we are shipping Amyloid beta (A4) Precursor-Like Protein 2 Kits (11) and Amyloid beta (A4) Precursor-Like Protein 2 Proteins (9) and many more products for this protein. A total of 117 Amyloid beta (A4) Precursor-Like Protein 2 products are currently listed.
Synonyms:
AI790698, APLP-2, APLP2, aplp2 A, aplp2 B, Apph, APPL2, CDEBP, MGC86389, si:dkey-11k4.3, WALPLP2
list all antibodies Gene Name GeneID UniProt
APLP2 334 Q06481
APLP2 11804 Q06335
APLP2 64312  

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Most Popular Reactivities for anti-Amyloid beta (A4) Precursor-Like Protein 2 (APLP2) Antibodies

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All available anti-Amyloid beta (A4) Precursor-Like Protein 2 Antibodies

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Top referenced anti-Amyloid beta (A4) Precursor-Like Protein 2 Antibodies

  1. Human Polyclonal APLP2 Primary Antibody for EIA, WB - ABIN950473 : Tuli, Sharma, Capek, Naslavsky, Caplan, Solheim: Mechanism for amyloid precursor-like protein 2 enhancement of major histocompatibility complex class I molecule degradation. in The Journal of biological chemistry 2009 (PubMed)
    Show all 5 references for ABIN950473

  2. Human Polyclonal APLP2 Primary Antibody for IHC (p), WB - ABIN658567 : Tuli, Sharma, McIlhaney, Talmadge, Naslavsky, Caplan, Solheim: Amyloid precursor-like protein 2 increases the endocytosis, instability, and turnover of the H2-K(d) MHC class I molecule. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
    Show all 3 references for ABIN658567

  3. Human Polyclonal APLP2 Primary Antibody for IHC, ELISA - ABIN1532122 : Sprecher, Grant, Grimm, OHara, Norris, Norris, Foster: Molecular cloning of the cDNA for a human amyloid precursor protein homolog: evidence for a multigene family. in Biochemistry 1993 (PubMed)

More Antibodies against Amyloid beta (A4) Precursor-Like Protein 2 Interaction Partners

Zebrafish Amyloid beta (A4) Precursor-Like Protein 2 (APLP2) interaction partners

  1. these results indicate the Appa (show APP Antibodies)-RFP (show MKRN1 Antibodies) and Aplp2 fusion proteins are likely secreted from the central nervous system and accumulate in the embryonic veins independent of blood flow.

Human Amyloid beta (A4) Precursor-Like Protein 2 (APLP2) interaction partners

  1. This paper demonstrates an important role for APLP2 in refractive development in mice and humans, suggesting a high level of evolutionary conservation of the signaling pathways underlying refractive eye development.

  2. Data show that amyloid precursor-like protein 2 (APLP2) expression is elevated in pancreatic cancer metastases.

  3. We conclude that PCSK9 (show PCSK9 Antibodies) enhances the degradation of the LDLR (show LDLR Antibodies) independently of either APLP2 or sortilin (show SORT1 Antibodies) both ex vivo and in mice.

  4. APLP1 (show APLP1 Antibodies) and APLP2, behave similarly to APP (show APP Antibodies) in that they both associate with assembled NMDA receptors in the endoplasmic reticulum

  5. our discoveries establish a role for APLP2 in the growth of pancreatic cancer cells and show that inhibitors preventing APLP2 cleavage reduce the viability of pancreatic cancer cells.

  6. amyloid precursor protein-like (show APP Antibodies) protein-2, but not amyloid precursor protein (show APP Antibodies), is involved in mediating postendocytic delivery of PCSK9 (show PCSK9 Antibodies) to lysosomes and is therefore important for PCSK9 (show PCSK9 Antibodies) function

  7. Aberrant enhancement of YWK-II/APLP2 by nuclear export of Bat3 (show BAT3 Antibodies) may play a role in cancer development by inhibiting cell apoptosis.

  8. APP (show APP Antibodies) and its mammalian homologs, amyloid precursor-like proteins APLP1 (show APLP1 Antibodies) and APLP2, participate under physiological conditions via trans-cellular dimerization in synaptogenesis.

  9. APLP-2 (and APLP1 (show APLP1 Antibodies)) are capable of activating gene transcription via binding to Mint3 (show APBA3 Antibodies).

  10. Regulation of major histocompatibility complex class I molecule expression on cancer cells by amyloid precursor-like protein 2.

Mouse (Murine) Amyloid beta (A4) Precursor-Like Protein 2 (APLP2) interaction partners

  1. These data support the notion that APP (show APP Antibodies) and APLP2 facilitate transmitter release, likely through the interaction with the neurotransmitter release machinery.

  2. This paper demonstrates an important role for APLP2 in refractive development in mice and humans, suggesting a high level of evolutionary conservation of the signaling pathways underlying refractive eye development.

  3. Study provides compelling evidence for an essential role of both APP (show APP Antibodies) and APLP2 for neuronal and synaptic morphology as well as hippocampal function and suggest an acute and specific function of endogenous APPsalpha to facilitate synaptic plasticity

  4. The study investigates the subcellular distribution patterns of the metal ions Cu, Zn, Fe, and Ca in individual neurons derived from APP (show APP Antibodies) and APLP2 knockout mice brains to further define their role in metal homeostasis.

  5. This study further highlights the distinct and essential role of APLP2 at NMJ synapses that cannot be compensated by APP (show APP Antibodies).

  6. Amyloid precursor protein (APP)/APP-like (show APP Antibodies) protein 2 (APLP2) expression is required to initiate endosome-nucleus-autophagosome

  7. The study investigated copper, iron, zinc and manganese levels in APP (show APP Antibodies) and APLP-2 single knockout mice as well as homozygous:hemizygous knockout mice at 3, 12 and 18 plus months of age.

  8. Data reveal that APLP2 is specifically required for proper cell cycle exit of neuronal progenitors, and thus has a distinct role in priming cortical progenitors for neuronal differentiation.

  9. APLP2 and the intracellular domain of APP (show APP Antibodies) are not essential for coherent activity patterns in the hippocampus, but have subtle effects on synaptic plasticity and fine-tuning of network oscillations.

  10. Gain and loss of function experiments demonstrate that miR (show MLXIP Antibodies)-153 suppresses expression of amyloid precursor protein (APP (show APP Antibodies)) and APLP2.

Amyloid beta (A4) Precursor-Like Protein 2 (APLP2) Antigen Profile

Antigen Summary

This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with Amyloid beta (A4) Precursor-Like Protein 2 (APLP2)

  • amyloid beta (A4) precursor-like protein 2 (aplp2-b) antibody
  • amyloid beta (A4) precursor-like protein 2 (APLP2) antibody
  • adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 (APPL2) antibody
  • amyloid beta (A4) precursor-like protein 2 (aplp2) antibody
  • amyloid beta (A4) precursor-like protein 2 (Aplp2) antibody
  • AI790698 antibody
  • APLP-2 antibody
  • APLP2 antibody
  • aplp2 A antibody
  • aplp2 B antibody
  • Apph antibody
  • APPL2 antibody
  • CDEBP antibody
  • MGC86389 antibody
  • si:dkey-11k4.3 antibody
  • WALPLP2 antibody

Protein level used designations for APLP2

amyloid beta (A4) precursor-like protein 2 , amyloid-beta-like protein B , DIP13 beta , adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 , suppression of tumorigenicity 14 , amyloid-like protein 2 , DCC-interacting protein 13-beta-like , amyloid-like protein 2-like , amyloid-beta-like protein A , CDEI box-binding protein , amyloid precursor protein homolog HSD-2 , CDEBP , Amyloid protein precursor-like protein 2 , amyloid beta (A4) precursor-like protein 2-like , sperm membrane protein (YWK-II) , sperm membrane protein YWK-II

GENE ID SPECIES
431789 Xenopus laevis
452197 Pan troglodytes
479393 Canis lupus familiaris
481297 Canis lupus familiaris
718819 Macaca mulatta
741867 Pan troglodytes
785005 Bos taurus
796801 Danio rerio
100068170 Equus caballus
100072668 Equus caballus
100076773 Ornithorhynchus anatinus
100126835 Sus scrofa
100358231 Oryctolagus cuniculus
100380132 Xenopus (Silurana) tropicalis
100404192 Callithrix jacchus
100414190 Callithrix jacchus
100470064 Ailuropoda melanoleuca
100477041 Ailuropoda melanoleuca
431790 Xenopus laevis
100557178 Anolis carolinensis
334 Homo sapiens
11804 Mus musculus
64312 Rattus norvegicus
419727 Gallus gallus
100190991 Sus scrofa
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